Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | CACNA1S | Q13698 | 5/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | STAT6 | P42226 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4675287 | 1.00 | KDM4E (0.36) | KDM4EHKDC1CACNA1SBRAFCYP3A4 | |
| SCHEMBL4671531 | 1.00 | KDM4E (0.36) | KDM4EHKDC1CACNA1SBRAFCYP3A4 | |
| SCHEMBL4677221 | 0.85 | KDM4E (0.34) | KDM4EHKDC1BRAFTSHRCYP19A1 | |
| SCHEMBL4673211 | 0.84 | KDM4E (0.41) | KDM4EHKDC1BRAFTSHRCYP19A1 | |
| SCHEMBL4674838 | 0.84 | KDM4E (0.41) | KDM4EHKDC1BRAFTSHRCYP19A1 | |
| SCHEMBL4673235 | 0.82 | NPSR1 (0.42) | KDM4EHKDC1CACNA1STSHRLMNA | |
| SCHEMBL4673240 | 0.82 | NPSR1 (0.42) | KDM4EHKDC1CACNA1STSHRLMNA | |
| SCHEMBL4673246 | 0.82 | NPSR1 (0.42) | KDM4EHKDC1CACNA1STSHRLMNA | |
| SCHEMBL4671101 | 0.70 | SMN1; SMN2 (0.57) | KDM4EHKDC1TSHRLMNAALDH1A1 | |
| SCHEMBL4671613 | 0.69 | NPSR1 (0.41) | KDM4EHKDC1TSHRHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1375495-B1 | METHOD FOR PRODUCING A 2-AZETIDINONE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2008-09-03 | — | — | EP | disclosed |
| US-7126003-B2 | Method for producing 2-azetidinone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-10-24 | — | — | US | disclosed |
| US-20040072309-A1 | Method for producing 2-azetidinone derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2004-04-15 | — | — | US | disclosed |
| EP-1375495-A1 | METHOD FOR PRODUCING 2-AZETIDINONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072309-A1 | Method for producing 2-azetidinone derivative | CYP51A1, AZI2, POR | KDM4E 1139/4885HKDC1 2326/4885CACNA1S 4588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.