Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | FPR2 | P25090 | 2/20 | 0.34 |
| ▸ | DDX3X | O00571 | 1/20 | 0.34 |
| ▸ | FPR3 | P25089 | 1/20 | 0.34 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.33 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4817839 | 0.68 | GRM5 (0.39) | GRM5NPSR1FPR2DDX3XFPR3 | |
| SCHEMBL4673438 | 0.68 | FPR2 (0.40) | GRM5NPSR1FPR2DDX3XFPR3 | |
| SCHEMBL31637545 | 0.67 | FPR2 (0.36) | FPR2FPR3NPC1RAB9A | |
| SCHEMBL4669013 | 0.65 | SYK (0.39) | GRM5NPSR1FPR2DDX3XFPR3 | |
| SCHEMBL4007229 | 0.64 | NPSR1 (0.54) | NPSR1FPR2KCNQ3KCNQ2NPC1 | |
| Hydrochloric Acid SCHEMBL4821983 | 0.64 | SYK (0.39) | GRM5FPR2FPR3SYK | |
| SCHEMBL20038016 | 0.63 | NPSR1 (0.42) | GRM5NPSR1KCNQ3KCNQ2SYK | |
| SCHEMBL30421055 | 0.62 | NPSR1 (0.55) | NPSR1KCNQ3KCNQ2NPC1RAB9A | |
| SCHEMBL1430701 | 0.62 | NPSR1 (0.55) | NPSR1KCNQ3KCNQ2NPC1RAB9A | |
| SCHEMBL3632606 | 0.62 | ADRA2A (0.50) | NPSR1KCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757586-B1 | POLYSBUSTITUIRTE 1,1-PYRIDINYLAMINOCYCLOPROPANAMIN DERIVATE, VERFAHREN ZU DEREN HERSTELLUNG UND DIESE ENTHALTENDE PHARMATUETISCHE ZUSAMMENSETZUNG | SERVIER LAB (FR) | 2008-12-03 | — | — | EP | disclosed |
| EP-1757586-A1 | POLYSBUSTITUIRTE 1,1-PYRIDINYLAMINOCYCLOPROPANAMIN DERIVATE, VERFAHREN ZU DEREN HERSTELLUNG UND DIESE ENTHALTENDE PHARMATUETISCHE ZUSAMMENSETZUNG | Les Laboratoires Servier (FR) | 2007-02-28 | — | — | EP | disclosed |
| WO-2007012761-A1 | NOVEL POLYSUBSTITUTED 1,1-PYRIDINYL AMINOCYCLOPROPANAMINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2007-02-01 | — | — | WO | disclosed |