SCHEMBL1698197

SCHEMBL1698197

C=CC(=O)NOS(=O)(=O)CC(C)C

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
TGM2 P21980 3/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
ZDHHC20 Q5W0Z9 1/20 0.30
ZDHHC2 Q9UIJ5 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31435702 0.98 TSHR (0.38) TSHRTGM2ALDH1A1MAPK1TDP1
SCHEMBL6435238 0.98 TSHR (0.38) TSHRTGM2ALDH1A1MAPK1TDP1
SCHEMBL10584159 0.88 TSHR (0.38) TSHRTGM2ALDH1A1MAPK1TDP1
SCHEMBL28866456 0.85 TSHR (0.36) TSHRTGM2ALDH1A1MAPK1TDP1
SCHEMBL28029618 0.83 TSHR (0.37) TSHRALDH1A1MAPK1TDP1
SCHEMBL4673569 0.81 TSHR (0.38) TSHRTGM2ALDH1A1MAPK1TDP1
SCHEMBL10714172 0.79 TSHR (0.35) TSHRTGM2ALDH1A1MAPK1TDP1
SCHEMBL22318956 0.78 ZDHHC20 (0.42) TSHRALDH1A1MAPK1MEN1KMT2A
SCHEMBL27871882 0.78 ZDHHC20 (0.42) TSHRALDH1A1MAPK1MEN1KMT2A
SCHEMBL28452644 0.78 ZDHHC20 (0.42) TSHRALDH1A1MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230216082-A1 POLYELECTROLYTE COMPOSITES FIRST-CITIZENS BANK & TRUST COMPANY 2023-07-06 US claimed
EP-3893833-A1 PERFUME GEL L'OREAL (FR) 2021-10-20 EP claimed
EP-3727305-A1 OIL-IN-WATER EMULSION FOR MAKING UP AND CARING FOR THE LIPS LVMH Recherche (FR) 2020-10-28 EP claimed
WO-2020209831-A1 STABLE SUSPENSION OF ELASTOMER PARTICLES FOR USE IN A CEMENT SLURRY HALLIBURTON ENERGY SERVICES, INC. (US) 2020-10-15 WO claimed
WO-2020120704-A1 PERFUME GEL L'OREAL (FR) 2020-06-18 WO claimed
US-20100047156-A1 MULTIPLE STAGE REVERSE OSMOSIS METHOD FOR REMOVING BORON FROM A SALINATED FLUID MEKOROT ISRAEL NATIONAL WATER COMPANY, LTD. (IL) 2010-02-25 US claimed
EP-1570836-B1 Transparent self-tanning gel comprising a hydrosoluble or hydrodispersible polymer of acrylamido 2-methyl propane sulfonic acid OREAL (FR) 2008-03-26 EP claimed
WO-2008020444-A1 MULTIPLE STAGE REVERSE OSMOSIS METHOD FOR REMOVING BORON FROM A SALINATED FLUID MEKOROT ISRAEL NATIONAL WATER COMPANY, LTD. (IL) 2008-02-21 WO claimed
EP-1570836-A1 Transparent self-tanning gel comprising a hydrosoluble or hydrodispersible polymer of acrylamido 2-methyl propane sulfonic acid L'OREAL (FR) 2005-09-07 EP claimed
US-11998629-B2 Method for dyeing keratinous material, comprising the use of an organosilicon compound, an effect pigment and a film-forming polymer HENKEL AG & CO. KGAA (US) 2024-06-04 US disclosed
US-20240165005-A1 METHOD FOR DYEING KERATINOUS MATERIAL, INCLUDING THE APPLICATION OF AN ORGANOSILICON COMPOUND, A DYEING COMPOUND, A SEALING REAGENT AND AN ALKALINE PRE-TREATMENT AGENT HENKEL AG & CO. KGAA (DE) 2024-05-23 US disclosed
WO-2024094892-A1 TITANATE SCALE INHIBITION IN A SINGLE STREAM BAYER PROCESS CYTEC INDUSTRIES INC. (US) 2024-05-10 WO disclosed
WO-2024016587-A1 WATER-BASED BINDER, AND PREPARATION METHOD THEREFOR AND USE THEREOF 深圳市研一新材料有限责任公司 2024-01-25 WO disclosed
US-20230270652-A1 METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, A PHOSPHORIC ACID ESTER AND A DYEING COMPOUND HENKEL AG & CO. KGAA (DE) 2023-08-31 US disclosed
EP-0540237-A2 Superabsorbent polymeric materials which are temperature and salt tolerant and cables which include same AT&T Corp. (US) 1993-05-05 EP disclosed
US-5163115-A Anionic polymers containing sulfonate, sulfate or phosphate groups AT&T BELL LABORATORIES (US) 1992-11-10 US disclosed
EP-0372746-A2 The use of selected amphiphilic copolymers in the treatment of leather ROHM AND HAAS COMPANY (US) 1990-06-13 EP disclosed
EP-0309049-A1 Method for controlling calcium carbonate scaling in high PH aqueous systems using carboxylic/sulfonic polymers CALGON CORPORATION (US) 1989-03-29 EP disclosed
EP-0302651-A1 Method for controlling calcium carbonate scaling in high PH aqueous systems CALGON CORPORATION (US) 1989-02-08 EP disclosed
US-4647382-A ACRYLAMIDE-ACRYLAMIDO-2-METHYL-1-PROPANESULFONIC ACID COPOLYMER SHARPE ANDREW J JR (US) 1987-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230270652-A1 METHOD FOR DYEING KERATINOUS MATERIAL, COMPRISING THE USE OF AN ORGANOSILICON COMPOUND, A PHOSPHORIC ACID ESTER AND A DYEING COMPOUND KRT18, ALPG, DSG1 TSHR 4847/4885TGM2 2216/4885ALDH1A1 510/4885
US-11998629-B2 Method for dyeing keratinous material, comprising the use of an organosilicon compound, an effect pigment and a film-forming polymer KRT18, KIT, EPCAM TSHR 4707/4885TGM2 2118/4885ALDH1A1 2633/4885
US-20240165005-A1 METHOD FOR DYEING KERATINOUS MATERIAL, INCLUDING THE APPLICATION OF AN ORGANOSILICON COMPOUND, A DYEING COMPOUND, A SEALING REAGENT AND AN ALKALINE PRE-TREATMENT AGENT KRT18, DSG1, PCNA TSHR 4832/4885TGM2 622/4885ALDH1A1 291/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.