Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | PAM | P19021 | 1/20 | 0.49 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28942424 | 0.88 | ALDH1A1 (0.65) | ALDH1A1MAPK1L3MBTL1PAMENPP2 | |
| SCHEMBL4675591 | 0.87 | ALDH1A1 (0.79) | ALDH1A1MAPK1L3MBTL1PAMENPP2 | |
| SCHEMBL1724245 | 0.84 | ALDH1A1 (0.69) | ALDH1A1MAPK1L3MBTL1PAMENPP2 | |
| SCHEMBL56760 | 0.83 | ALDH1A1 (0.73) | ALDH1A1MAPK1L3MBTL1PAMENPP2 | |
| SCHEMBL27499661 | 0.83 | ALDH1A1 (0.92) | ALDH1A1MAPK1L3MBTL1PAMENPP2 | |
| SCHEMBL361779 | 0.82 | ALDH1A1 (1.00) | ALDH1A1MAPK1L3MBTL1PAMENPP2 | |
| SCHEMBL1125421 | 0.82 | CYP4F2 (0.48) | ALDH1A1MAPK1L3MBTL1PAMKMT2A | |
| SCHEMBL31074140 | 0.82 | CYP4F2 (0.48) | ALDH1A1MAPK1L3MBTL1PAMKMT2A | |
| SCHEMBL6784181 | 0.81 | ALDH1A1 (0.96) | ALDH1A1MAPK1L3MBTL1PAMENPP2 | |
| SCHEMBL5441092 | 0.81 | ALDH1A1 (0.69) | ALDH1A1MAPK1L3MBTL1PAMENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663936-B1 | BIARYLOXYMETHYLARENE-CARBOXYLIC ACIDS | HOFFMANN LA ROCHE (CH) | 2008-01-09 | — | — | EP | disclosed |