SCHEMBL4674255

SCHEMBL4674255

CN1CCCC2CC=CC=C21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23047083 1.00
SCHEMBL1240961 0.89
SCHEMBL11440182 0.78 DRD2 (0.38)
SCHEMBL9432506 0.78
SCHEMBL6114034 0.78
SCHEMBL11789421 0.77 DRD2 (0.30)
SCHEMBL31542154 0.76 NOS3 (0.32)
SCHEMBL11660093 0.76 DRD2 (0.33)
SCHEMBL9355576 0.75 SLC18A3 (0.31)
SCHEMBL14797690 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116239529-B Preparation method of N-methyltetrahydroquinoline alkaloid with participation of carbon dioxide 山西大学 2024-05-24 CN claimed
CN-116239529-A Preparation method of N-methyltetrahydroquinoline alkaloid with participation of carbon dioxide 山西大学 2023-06-09 CN claimed
EP-1461330-B1 3H-NAPHTHO[2,1-b]-PYRANE DERIVATIVES AND THEIR USE RODENSTOCK GMBH (DE) 2008-03-12 EP claimed
CN-116768733-B Aryl cyclic ammonium salt arylation and silicon-based method 中国科学技术大学 2025-05-23 CN disclosed
CN-116239529-B Preparation method of N-methyltetrahydroquinoline alkaloid with participation of carbon dioxide 山西大学 2024-05-24 CN disclosed
CN-116239529-B Preparation method of N-methyltetrahydroquinoline alkaloid with participation of carbon dioxide 山西大学 2024-05-24 CN disclosed
CN-116239529-B Preparation method of N-methyltetrahydroquinoline alkaloid with participation of carbon dioxide 山西大学 2024-05-24 CN disclosed
CN-117160451-A Platinum-tin bimetallic catalyst for quinoline compound reduction methylation and preparation method and application thereof 浙江大学衢州研究院 2023-12-05 CN disclosed
CN-116768733-A Aryl cyclic ammonium salt arylation and silicon-based method 中国科学技术大学 2023-09-19 CN disclosed
CN-116239529-A Preparation method of N-methyltetrahydroquinoline alkaloid with participation of carbon dioxide 山西大学 2023-06-09 CN disclosed
CN-116239529-A Preparation method of N-methyltetrahydroquinoline alkaloid with participation of carbon dioxide 山西大学 2023-06-09 CN disclosed
CN-107098846-B N-acyl sulfonamide FBPase inhibitor, preparation method thereof, pharmaceutical composition and application thereof 中国医学科学院药物研究所 2020-10-09 CN disclosed
CN-107098846-A N- acyl sulfonamides class FBPase inhibitor, its preparation method, pharmaceutical composition and purposes 中国医学科学院药物研究所 2017-08-29 CN disclosed
CN-102675206-A Preparation method of novel acetylcholinesterase inhibitor, and activity thereof UNIV CENTRAL SOUTH 2012-09-19 CN disclosed
US-4500715-A CHEMICAL INTERMEDIATES FOR PLANT SAFENING AGENTS AND DYES BAYER AKTIENGESELLSCHAFT (DE) 1985-02-19 US disclosed
US-4377652-A PARTICLES DISPERSED IN A POLYMER BASED ON AN AROMATIC DIAMINE AND TRIMELLITIC ACID OR DERIVATIVE; DIELECTRICS; SUBSTRATES; PRINTED CIRCUITS ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1983-03-22 US disclosed
US-4348330-A Process for the production of sulphinates of benzhydrol compounds CIBA-GEIGY CORPORATION (US) 1982-09-07 US disclosed
US-4268438-A Cationic 1,3,4-thiadiazole dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1981-05-19 US disclosed
US-4211436-A Pressure-sensitive recording material BAYER AKTIENGESELLSCHAFT (DE) 1980-07-08 US disclosed
US-3948877-A POLYACRYLONITRILE, ACID MODIFIED POLYESTERS OR POLYAMIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-04-06 US disclosed