⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2326557 | 0.79 | — | — | |
| SCHEMBL23851485 | 0.78 | KMT2A (0.56) | — | |
| SCHEMBL80874 | 0.78 | — | — | |
| SCHEMBL7098541 | 0.78 | TP53 (0.46) | — | |
| SCHEMBL10442620 | 0.74 | — | — | |
| SCHEMBL942463 | 0.74 | — | — | |
| SCHEMBL4088167 | 0.74 | — | — | |
| SCHEMBL12779618 | 0.74 | ALOX5 (0.42) | — | |
| SCHEMBL919847 | 0.74 | — | — | |
| SCHEMBL141900 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354931-A | Substituted oxazole derivative and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-30 | — | — | CN | disclosed |
| US-10308610-B2 | Inhibitor compounds of phosphodiesterase type 10A | AbbVie Deutschland GmbH & Co. KG (DE) | 2019-06-04 | — | — | US | disclosed |
| US-20180099936-A1 | NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A | AbbVie Deutschland GmbH & Co. KG (DE) | 2018-04-12 | — | — | US | disclosed |
| US-9856220-B2 | Inhibitor compounds of phosphodiesterase type 10A | AbbVie Deutschland GmbH & Co. KG (DE) | 2018-01-02 | — | — | US | disclosed |
| EP-3169671-A1 | SUBSTITUTED UREA DERIVATIVES AND PHARMACEUTICAL USES THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2017-05-24 | — | — | EP | disclosed |
| EP-2780324-B1 | HETEROCYCLIC CARBOXAMIDES USEFUL AS INHIBITORS OF PHOSPHODIESTERASE TYPE 10A | ABBVIE DEUTSCHLAND (DE) | 2017-05-17 | — | — | EP | disclosed |
| US-20160318871-A1 | NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A | ABBVIE INC. | 2016-11-03 | — | — | US | disclosed |
| WO-2016008433-A1 | SUBSTITUTED UREA DERIVATIVES AND PHARMACEUTICAL USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-01-21 | — | — | WO | disclosed |
| EP-2511257-B1 | Composition comprising an alpha ketoamide compound as cysteine protease inhibitor | VIROBAY INC (US) | 2015-06-17 | — | — | EP | disclosed |
| EP-2875001-A1 | NITROGENOUS HETEROCYCLIC DERIVATIVES AND THEIR APPLICATION IN DRUGS | Sunshine Lake Pharma Co., Ltd. (CN) | 2015-05-27 | — | — | EP | disclosed |
| US-5770579-A | Erythromycin compounds | ROUSSEL UCLAF (FR) | 1998-06-23 | — | — | US | disclosed |
| EP-0838453-A1 | HETEROCYCLIC CARBOXYLIC ACID DERIVATIVES AND DRUGS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 1998-04-29 | — | — | EP | disclosed |
| US-5561118-A | ANTIBIOTICS | ROUSSEL UCLAF (FR) | 1996-10-01 | — | — | US | disclosed |
| EP-0487411-B1 | Erythromycin derivatives, their preparation, intermediates obtained and their application as medicaments | ROUSSEL UCLAF (FR) | 1996-01-31 | — | — | EP | disclosed |
| US-5444051-A | BACTERICIDES | ROUSSEL UCLAF (FR) | 1995-08-22 | — | — | US | disclosed |
| EP-0602242-A1 | BENZISOXAZOLE COMPOUND AND USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0487411-A1 | Erythromycin derivatives, their preparation, intermediates obtained and their application as medicaments | ROUSSEL UCLAF (FR) | 1992-05-27 | — | — | EP | disclosed |
| EP-0033255-B1 | OXIMES DERIVED FROM ERYTHROMYCIN A, THEIR PREPARATION, THEIR APPLICATION IN PHARMACEUTICALS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1984-08-29 | — | — | EP | disclosed |
| US-4349545-A | Novel erythromycin a derivatives | ROUSSEL UCLAF (FR) | 1982-09-14 | — | — | US | disclosed |
| EP-0033255-A1 | Oximes derived from erythromycin A, their preparation, their application in pharmaceuticals and pharmaceutical compositions containing them | ROUSSEL-UCLAF (FR) | 1981-08-05 | — | — | EP | disclosed |