Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | CA12 | O43570 | 4/20 | 0.36 |
| ▸ | CA9 | Q16790 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29478204 | 1.00 | NQO1 (0.44) | NQO1MAOAMAOBNCOA1CYP2A6 | |
| SCHEMBL6782718 | 0.77 | MAOA (0.43) | MAOAMAOBNCOA1CYP2A6MAPT | |
| SCHEMBL14627838 | 0.77 | NQO1 (0.44) | NQO1MAOAMAOBNCOA1CYP2A6 | |
| SCHEMBL3860557 | 0.77 | ALDH1A1 (0.44) | MAOAMAOBNCOA1CYP2A6MAPT | |
| SCHEMBL13891558 | 0.77 | ALDH1A1 (0.50) | NQO1MAOAMAOBNCOA1CYP2A6 | |
| SCHEMBL8247621 | 0.77 | CYP2A6 (0.43) | MAOAMAOBNCOA1CYP2A6ALDH1A1 | |
| SCHEMBL999261 | 0.74 | CYP3A4 (0.42) | MAOAMAOBNCOA1CYP2A6MAPT | |
| SCHEMBL9479907 | 0.74 | ALDH1A1 (0.41) | NQO1MAOAMAOBCYP2A6MAPT | |
| SCHEMBL998144 | 0.73 | MAOA (0.40) | MAOAMAOBNCOA1CYP2A6MAPT | |
| SCHEMBL2670683 | 0.72 | NQO1 (0.62) | NQO1MAOAMAOBNCOA1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8377985-B2 | Treatment of cancer | BIPAR SCIENCES, INC. (US) | 2013-02-19 | — | — | US | claimed |
| EP-2387403-A1 | METHOD OF TREATING CANCER | Academisch Medisch Centrum bij de Universiteit van Amsterdam (NL) | 2011-11-23 | — | — | EP | claimed |
| US-20110253692-A1 | Electrical heater for vehicle windshields and windows | SCHAUBLE RICHARD EGON | 2011-10-20 | — | — | US | claimed |
| JP-2011500684-A | — | — | 2011-01-06 | — | — | JP | claimed |
| CN-101903025-A | Utilize benzopyrone-type PARP inhibitor for treating method for cancer and compositions | BIPAR SCIENCES INC | 2010-12-01 | — | — | CN | claimed |
| EP-2211854-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER USING BENZOPYRONE-TYPE PARP INHIBITORS | BiPar Sciences, Inc. (US) | 2010-08-04 | — | — | EP | claimed |
| WO-2010082821-A1 | METHOD OF TREATING CANCER | ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM (NL) | 2010-07-22 | — | — | WO | claimed |
| WO-2010082813-A1 | METHOD OF TREATING CANCER | ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM (NL) | 2010-07-22 | — | — | WO | claimed |
| EP-1009404-A4 | METHODS FOR TREATING INFLAMMATION AND INFLAMMATORY DISEASES USING pADPRT INHIBITORS | OCTAMER INC (US) | 2009-07-01 | — | — | EP | claimed |
| US-20090149417-A1 | Methods and compositions for the treatment of cancer using benzopyrone-type PARP inhibitors | BIPAR SCIENCES, INC. | 2009-06-11 | — | — | US | claimed |
| WO-2009051815-A1 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF CANCER USING BENZOPYRONE-TYPE PARP INHIBITORS | BIPAR SCIENCES, INC. (US) | 2009-04-23 | — | — | WO | claimed |
| US-20080319054-A1 | Treatment of Cancer | BIPAR SCIENCES, INC. | 2008-12-25 | — | — | US | claimed |
| EP-1009404-A1 | METHODS FOR TREATING INFLAMMATION AND INFLAMMATORY DISEASES USING pADPRT INHIBITORS | Octamer, Inc. (US) | 2000-06-21 | — | — | EP | claimed |
| WO-1998051308-A1 | METHODS FOR TREATING INFLAMMATION AND INFLAMMATORY DISEASES USING pADPRT INHIBITORS | OCTAMER, INC. (US) | 1998-11-19 | — | — | WO | claimed |
| EP-0533902-A1 | A METHOD FOR INHIBITION OF RETROVIRAL REPLICATION | OCTAMER, INC. (US) | 1993-03-31 | — | — | EP | claimed |
| WO-1992018123-A2 | A METHOD FOR INHIBITION OF RETROVIRAL REPLICATION | OCTAMER, INC. (US) | 1992-10-29 | — | — | WO | claimed |
| US-20250381221-A1 | Compositions and Methods for Treating Cancer | IN8BIO INC (US) | 2025-12-18 | — | — | US | disclosed |
| US-20250161247-A1 | METHOD FOR TREATING BREAST CANCERS AND PARP RESISTANT BREAST CANCERS | LANTERN PHARMA INC. (US) | 2025-05-22 | — | — | US | disclosed |
| WO-1992018123-A2 | A METHOD FOR INHIBITION OF RETROVIRAL REPLICATION | OCTAMER, INC. (US) | 1992-10-29 | — | — | WO | disclosed |
| WO-1992006687-A1 | NOVEL 5-IODO-6-AMINO-1,2-BENZOPYRONES AND THEIR ANALOGS USEFUL AS CYTOSTATIC AND ANTIVIRAL AGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250161247-A1 | METHOD FOR TREATING BREAST CANCERS AND PARP RESISTANT BREAST CANCERS | PARP1, PARP2, PARP3 | NQO1 457/4885MAOA 2310/4885MAOB 2213/4885 |
| US-20090149417-A1 | Methods and compositions for the treatment of cancer using benzopyrone-type PARP inhibitors | PARP1, PARP2, PARP3 | NQO1 35/4885MAOA 1244/4885MAOB 802/4885 |
| US-20080319054-A1 | Treatment of Cancer | PARP1, PARP2, PARP3 | NQO1 55/4885MAOA 1717/4885MAOB 1577/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.