⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10686390 | 0.67 | — | — | |
| SCHEMBL4302331 | 0.54 | — | — | |
| SCHEMBL164168 | 0.53 | — | — | |
| SCHEMBL22932831 | 0.53 | — | — | |
| SCHEMBL7928126 | 0.51 | — | — | |
| SCHEMBL20536224 | 0.47 | — | — | |
| SCHEMBL2386932 | 0.47 | — | — | |
| SCHEMBL87532 | 0.46 | — | — | |
| SCHEMBL15544478 | 0.46 | — | — | |
| SCHEMBL722089 | 0.45 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221691-B | Methylenedioxybenzo [ b ] [1,4] diazepine [5,6-e ] triazinone derivative and pharmaceutically acceptable salt, preparation method and application thereof | 常熟理工学院 | 2024-10-15 | — | — | CN | claimed |
| CN-118221691-A | Methylenedioxybenzo [ b ] [1,4] diazepine [5,6-e ] triazinone derivative and pharmaceutically acceptable salt, preparation method and application thereof | 常熟理工学院 | 2024-06-21 | — | — | CN | claimed |
| EP-3386984-B1 | HEXAHYDROPYRAZINOTRIAZINONE DERIVATIVES AS KINASE INHIBITORS | UCB Biopharma SRL (BE) | 2021-08-11 | — | — | EP | claimed |
| CN-102421294-A | Defoliant containing thidiazuron and 1,2, 4-triazone | BAYER CROPSCIENCE AG | 2012-04-18 | — | — | CN | claimed |
| EP-1436267-B1 | LACTAM DERIVATIVES AS ANTAGONISTS FOR HUMAN 11CBY RECEPTORS | SMITHKLINE BEECHAM PLC (GB) | 2006-12-27 | — | — | EP | claimed |
| US-20050059651-A1 | Lactam derivatives as antagonists for human 11cby receptors | SMITHKLINE BEECHAM P.L.C. (GB) | 2005-03-17 | — | — | US | claimed |
| EP-1436267-A1 | LACTAM DERIVATIVES AS ANTAGONISTS FOR HUMAN 11CBY RECEPTORS | SMITHKLINE BEECHAM PLC (GB) | 2004-07-14 | — | — | EP | claimed |
| WO-2003033480-A1 | LACTAM DERIVATIVES AS ANTAGONISTS FOR HUMAN 11CBY RECEPTORS | SMITHKLINE BEECHAM PLC (GB) | 2003-04-24 | — | — | WO | claimed |
| CN-1308530-A | Use of tricyclic antidepressants for local analgesia | UNIV DALHOUSIE (CA) | 2001-08-15 | — | — | CN | claimed |
| WO-2026104678-A1 | NOVEL SULFONAMIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2026-05-21 | — | — | WO | disclosed |
| CN-118221691-B | Methylenedioxybenzo [ b ] [1,4] diazepine [5,6-e ] triazinone derivative and pharmaceutically acceptable salt, preparation method and application thereof | 常熟理工学院 | 2024-10-15 | — | — | CN | disclosed |
| CN-118221691-A | Methylenedioxybenzo [ b ] [1,4] diazepine [5,6-e ] triazinone derivative and pharmaceutically acceptable salt, preparation method and application thereof | 常熟理工学院 | 2024-06-21 | — | — | CN | disclosed |
| CN-117940166-A | SOS1 inhibitors and RAS inhibitors for the treatment of pain | 塞文莱斯治疗有限公司 | 2024-04-26 | — | — | CN | disclosed |
| CN-117794537-A | Solid dosage forms and dosing regimens comprising (2 r,3s,4s,5 r) -4- [ [3- (3, 4-difluoro-2-methoxy-phenyl) -4, 5-dimethyl-5- (trifluoromethyl) tetrahydrofuran-2-carbonyl ] amino ] pyridine-2-carboxamide | 沃泰克斯药物股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| WO-1999032652-A1 | MODIFICATION OF POLYSACCHARIDES BY MEANS OF A PHENOL OXIDIZING ENZYME | NOVO NORDISK A/S (DK) | 1999-07-01 | — | — | WO | disclosed |
| WO-1999024433-A1 | 2-PHENYL SUBSTITUTED IMIDAZOTRIAZINONES AS PHOSPHODIESTERASE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-05-20 | — | — | WO | disclosed |
| WO-1998011075-A1 | PYRAZINONES AND TRIAZINONES AND THEIR DERIVATIVES THEREOF | DU PONT PHARMACEUTICALS COMPANY (US) | 1998-03-19 | — | — | WO | disclosed |
| CN-1137221-A | Herbicidal compositions | RHONE POULENC AGRICULTURE (GB) | 1996-12-04 | — | — | CN | disclosed |
| EP-0207651-A2 | Anti-inflammatory 7-phenyl pyrazolo-[1,5A]-1,3,5-triazine derivatives | BIOMEASURE, INC. (US) | 1987-01-07 | — | — | EP | disclosed |
| US-4017259-A | TERT-AMINO-N-METHYLOL, DURABLE PRESS | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 1977-04-12 | — | — | US | disclosed |