Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 10/20 | 0.41 |
| ▸ | TOP2A | P11388 | 4/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4730859 | 1.00 | STAT3 (0.49) | STAT3MEN1KMT2AGSK3BTOP2A | |
| SCHEMBL9096957 | 0.91 | STAT3 (0.56) | STAT3MEN1KMT2AGSK3BTOP2A | |
| SCHEMBL8131981 | 0.91 | STAT3 (0.56) | STAT3MEN1KMT2AGSK3BTOP2A | |
| SCHEMBL8131449 | 0.91 | STAT3 (0.56) | STAT3MEN1KMT2AGSK3BTOP2A | |
| SCHEMBL8139161 | 0.86 | GSK3B (0.53) | STAT3MEN1KMT2AGSK3BTOP2A | |
| SCHEMBL8744082 | 0.86 | GSK3B (0.45) | STAT3MEN1KMT2AGSK3BTOP2A | |
| SCHEMBL5619172 | 0.86 | GSK3B (0.53) | STAT3MEN1KMT2AGSK3BTOP2A | |
| SCHEMBL4673103 | 0.86 | GSK3B (0.53) | STAT3MEN1KMT2AGSK3BTOP2A | |
| SCHEMBL7997875 | 0.86 | GSK3B (0.45) | STAT3MEN1KMT2AGSK3BTOP2A | |
| SCHEMBL8007897 | 0.86 | GSK3B (0.45) | STAT3MEN1KMT2AGSK3BTOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1304329-B1 | Pyridonecarboxylic acid derivatives and their use as antibacterial agents | DAIICHI SANKYO CO LTD (JP) | 2008-10-15 | — | — | EP | disclosed |
| EP-0807630-B1 | HETEROCYCLIC COMPOUNDS | DAIICHI SEIYAKU CO (JP) | 2003-05-07 | — | — | EP | disclosed |
| EP-1304329-A2 | Pyridonecarboxylic acid derivatives and their use as antibacterial agents | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-5849757-A | Pyridonecarboxylic acid derivatives substituted by a bicyclic amino group as antibacterials | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1998-12-15 | — | — | US | disclosed |
| EP-0807630-A1 | HETEROCYCLIC COMPOUNDS | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1997-11-19 | — | — | EP | disclosed |