Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 4/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | PNMT | P11086 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30643818 | 1.00 | HTR2B (0.51) | HTR2BHTR7RAB9ANPC1PNMT | |
| SCHEMBL8840922 | 0.87 | RAB9A (0.54) | HTR2BHTR7RAB9ANPC1PNMT | |
| SCHEMBL30616301 | 0.85 | RAB9A (0.49) | HTR2BHTR7RAB9ANPC1PNMT | |
| SCHEMBL20917777 | 0.85 | RAB9A (0.49) | HTR2BHTR7RAB9ANPC1PNMT | |
| SCHEMBL8655175 | 0.84 | RAB9A (0.48) | HTR2BHTR7RAB9ANPC1PNMT | |
| SCHEMBL2131214 | 0.84 | RAB9A (0.55) | HTR2BHTR7RAB9ANPC1PNMT | |
| SCHEMBL30695173 | 0.83 | RAB9A (0.47) | HTR2BHTR7RAB9ANPC1PNMT | |
| SCHEMBL20886929 | 0.81 | TOP1 (0.51) | HTR2BHTR7RAB9ANPC1PNMT | |
| SCHEMBL29112976 | 0.81 | RAB9A (0.46) | HTR2BHTR7RAB9ANPC1PNMT | |
| SCHEMBL20886942 | 0.80 | RAB9A (0.48) | HTR2BHTR7RAB9ANPC1PNMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7396936-B1 | Modulators of calcitonin and amylin receptor activity | KEMIA, INC. (US) | 2008-07-08 | — | — | US | disclosed |