SCHEMBL8840922

SCHEMBL8840922

O=C(Oc1cccc2c1Cc1ccccc1-2)Oc1cccc2c1Cc1ccccc1-2

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.54
NPC1 O15118 2/20 0.54
HTR2B P41595 3/20 0.47
HTR7 P34969 2/20 0.47
PNMT P11086 1/20 0.45
KDM4E B2RXH2 2/20 0.41
MAPK1 P28482 1/20 0.41
ALDH1A1 P00352 4/20 0.40
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
MAPT P10636 2/20 0.40
SRD5A2 P31213 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MAOA P21397 2/20 0.40
HTR2C P28335 2/20 0.40
CYP1A2 P05177 2/20 0.40
ADRA2A P08913 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
DRD2 P14416 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20917777 0.88 RAB9A (0.49) RAB9ANPC1HTR2BHTR7PNMT
SCHEMBL30616301 0.88 RAB9A (0.49) RAB9ANPC1HTR2BHTR7PNMT
SCHEMBL30643818 0.87 HTR2B (0.51) RAB9ANPC1HTR2BHTR7PNMT
SCHEMBL4675573 0.87 HTR2B (0.51) RAB9ANPC1HTR2BHTR7PNMT
SCHEMBL8655175 0.87 RAB9A (0.48) RAB9ANPC1HTR2BHTR7PNMT
SCHEMBL2131214 0.87 RAB9A (0.55) RAB9ANPC1HTR2BHTR7PNMT
SCHEMBL30695173 0.85 RAB9A (0.47) RAB9ANPC1HTR2BHTR7PNMT
SCHEMBL20886929 0.84 TOP1 (0.51) RAB9ANPC1HTR2BHTR7PNMT
SCHEMBL29112976 0.84 RAB9A (0.46) RAB9ANPC1HTR2BHTR7PNMT
SCHEMBL20886942 0.83 RAB9A (0.48) RAB9ANPC1HTR2BHTR7PNMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5633331-A TRANSPARENT, NONHYDROLYZING, IMPACT RESISTANT, DUCTILE THE DOW CHEMICAL COMPANY (US) 1997-05-27 US claimed
WO-1996029365-A1 VEHICLE EXTERIOR BODY PANELS PREPARED FROM DIARYL FLUORENE CARBONATE POLYMERS THE DOW CHEMICAL COMPANY (US) 1996-09-26 WO claimed
WO-1996029366-A1 BLENDS OF DIARYL FLUORENE CARBONATE POLYMERS WITH BISPHENOL A CARBONATE POLYMERS THE DOW CHEMICAL COMPANY (US) 1996-09-26 WO claimed
US-5486577-A HEAT RESISTANCE THE DOW CHEMICAL COMPANY (US) 1996-01-23 US claimed
US-8791211-B2 High refractive polymers, optical elements, and photoelectric device employing the same INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2014-07-29 US disclosed
CN-102101910-B Polymer and method for producing same, and optical element and photoelectric device comprising same IND TECH RES INST 2014-05-14 CN disclosed
US-20120197000-A1 HIGH REFRACTIVE POLYMERS, OPTICAL ELEMENTS, AND PHOTOELECTRIC DEVICE EMPLOYING THE SAME INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2012-08-02 US disclosed
CN-102617828-A High refractive index polymer, optical element comprising same, and photoelectric device IND TECH RES INST 2012-08-01 CN disclosed
CN-102101910-A Polymer and method for producing same, and optical element and photoelectric device comprising same IND TECH RES INST 2011-06-22 CN disclosed
US-5633331-A TRANSPARENT, NONHYDROLYZING, IMPACT RESISTANT, DUCTILE THE DOW CHEMICAL COMPANY (US) 1997-05-27 US disclosed
US-5633331-A TRANSPARENT, NONHYDROLYZING, IMPACT RESISTANT, DUCTILE THE DOW CHEMICAL COMPANY (US) 1997-05-27 US disclosed
US-5633331-A TRANSPARENT, NONHYDROLYZING, IMPACT RESISTANT, DUCTILE THE DOW CHEMICAL COMPANY (US) 1997-05-27 US disclosed
WO-1996029365-A1 VEHICLE EXTERIOR BODY PANELS PREPARED FROM DIARYL FLUORENE CARBONATE POLYMERS THE DOW CHEMICAL COMPANY (US) 1996-09-26 WO disclosed
WO-1996029365-A1 VEHICLE EXTERIOR BODY PANELS PREPARED FROM DIARYL FLUORENE CARBONATE POLYMERS THE DOW CHEMICAL COMPANY (US) 1996-09-26 WO disclosed
WO-1996029365-A1 VEHICLE EXTERIOR BODY PANELS PREPARED FROM DIARYL FLUORENE CARBONATE POLYMERS THE DOW CHEMICAL COMPANY (US) 1996-09-26 WO disclosed
WO-1996029366-A1 BLENDS OF DIARYL FLUORENE CARBONATE POLYMERS WITH BISPHENOL A CARBONATE POLYMERS THE DOW CHEMICAL COMPANY (US) 1996-09-26 WO disclosed
WO-1996029366-A1 BLENDS OF DIARYL FLUORENE CARBONATE POLYMERS WITH BISPHENOL A CARBONATE POLYMERS THE DOW CHEMICAL COMPANY (US) 1996-09-26 WO disclosed
US-5486577-A HEAT RESISTANCE THE DOW CHEMICAL COMPANY (US) 1996-01-23 US disclosed
US-5486577-A HEAT RESISTANCE THE DOW CHEMICAL COMPANY (US) 1996-01-23 US disclosed
US-5486577-A HEAT RESISTANCE THE DOW CHEMICAL COMPANY (US) 1996-01-23 US disclosed