SCHEMBL467571

SCHEMBL467571

CO[Si](OC)(OC)C(C)OC(N)=O

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.39
CHRM2 P08172 1/20 0.39
CHRM4 P08173 1/20 0.39
CHRM5 P08912 1/20 0.39
CHRM1 P11229 1/20 0.39
CHRM3 P20309 1/20 0.39
CYP2C9 P11712 1/20 0.39
TSHR P16473 1/20 0.39
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL141447 0.78 TSHR (0.48) CHRM2CHRM4CHRM1TSHRMAPT
SCHEMBL28278531 0.76 TSHR (0.46) CHRM2CHRM4CHRM1TSHRMAPT
SCHEMBL12814327 0.76 LMNA (0.39) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL5479880 0.76
SCHEMBL530525 0.75 LMNA (0.41) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL15364637 0.74 HCAR2 (0.45)
SCHEMBL28968175 0.73 ALDH1A1 (0.36) LMNA
SCHEMBL28995909 0.71 LMNA (0.36) LMNACHRM2CHRM4CHRM5CHRM1
SCHEMBL193159 0.71 ALDH1A1 (0.44) TSHR
SCHEMBL2702039 0.71 LMNA (0.35) LMNACHRM2CHRM4CHRM5CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108676540-A It is a kind of it is sprayable can brush seals glue and preparation method thereof 杭州之江新材料有限公司 2018-10-19 CN claimed
CN-108676540-A It is a kind of it is sprayable can brush seals glue and preparation method thereof 杭州之江新材料有限公司 2018-10-19 CN disclosed
CN-105073894-B Solidification compound 积水富乐株式会社 2018-06-08 CN disclosed
EP-2392600-B1 Polymer having a reactive silicon-containing group, methods for its preparation and a curable composition comprising the polymer KANEKA CORP (JP) 2015-12-23 EP disclosed
US-20120196981-A1 METHOD FOR PRODUCING a-HETERO-SUBSTITUTED ALKYLHALOHYDROSILANE AND USE THEREOF KANEKACORPORATION (JP) 2012-08-02 US disclosed
EP-2392600-A1 Polymer having a reactive silicon-containing group, methods for its preparation and a curable composition comprising the polymer Kaneka Corporation (JP) 2011-12-07 EP disclosed
EP-2386561-A1 Methods for producing alkoxyhydrosilanes Kaneka Corporation (JP) 2011-11-16 EP disclosed
US-8039142-B2 Battery case SONY CORPORATION (JP) 2011-10-18 US disclosed
US-20110207886-A1 Method for Producing a-hereto-Substituted Alkylhalohydrosilane and Use Thereof KANEKA CORPORATION (JP) 2011-08-25 US disclosed
EP-2308884-A1 METHOD FOR PRODUCING -HETERO-SUBSTITUTED ALKYLHALOHYDROSILANE AND USE THEREOF Kaneka Corporation (JP) 2011-04-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120196981-A1 METHOD FOR PRODUCING a-HETERO-SUBSTITUTED ALKYLHALOHYDROSILANE AND USE THEREOF ARSA, HACL2, AS3MT LMNA 1777/4885CHRM2 1963/4885CHRM4 1956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.