SCHEMBL4678092

SCHEMBL4678092

CC(C)OC(=O)C(C)(C)[NH]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 3/20 0.35
ADRA1A P35348 2/20 0.35
USP2 O75604 1/20 0.35
ABCB11 O95342 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
ADRB3 P13945 1/20 0.35
HPGD P15428 1/20 0.35
CNR1 P21554 1/20 0.35
ACHE P22303 1/20 0.35
SLC6A2 P23975 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4675760 0.81 TSHR (0.46) TSHRMEN1KMT2ALMNAADRA1A
SCHEMBL8093076 0.80 TSHR (0.40) TSHRMEN1KMT2ALMNAADRA1A
SCHEMBL6063978 0.78 TSHR (0.48) TSHRMEN1KMT2ALMNAADRA1A
SCHEMBL2478389 0.78 TSHR (0.48) TSHRMEN1KMT2ALMNAADRA1A
SCHEMBL4676285 0.77 MAPT (0.33) MAPT
SCHEMBL448528 0.76 TSHR (0.46) TSHRMEN1KMT2ALMNAADRA1A
SCHEMBL4675881 0.76 TSHR (0.46) TSHRMEN1KMT2ALMNAADRA1A
SCHEMBL4672400 0.75
SCHEMBL4673195 0.75 MEN1 (0.33) MEN1KMT2ATDP1
SCHEMBL12128600 0.74 TSHR (0.43) TSHRMEN1KMT2ALMNAADRA1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1095935-B1 6-Hydroxy-5,6-dihydrouracils as herbicides SUMITOMO CHEMICAL CO (JP) 2008-12-17 EP disclosed
US-6410484-B1 ACTIVE MATERIAL; CONTROLLING WEEDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-25 US disclosed
EP-1095935-A1 6-Hydroxy-5,6-dihydrouracils as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-05-02 EP disclosed