Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.61 |
| ▸ | PDGFRB | P09619 | 15/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311835 | 0.87 | SMN1; SMN2 (0.66) | FAAHPDGFRBMAPT | |
| SCHEMBL3723811 | 0.86 | CYP2C9 (0.65) | FAAHMAPT | |
| SCHEMBL4675018 | 0.84 | POLB (0.59) | FAAHMAPT | |
| SCHEMBL9467061 | 0.83 | MAPT (0.74) | FAAHPDGFRBMAPT | |
| SCHEMBL20236423 | 0.83 | FAAH (0.61) | FAAHPDGFRBMAPT | |
| SCHEMBL4676020 | 0.83 | POLB (0.73) | FAAHPDGFRBMAPT | |
| SCHEMBL4671482 | 0.83 | FAAH (0.67) | FAAHPDGFRBMAPT | |
| SCHEMBL22218259 | 0.82 | FAAH (0.60) | FAAHPDGFRBMAPT | |
| SCHEMBL28363630 | 0.81 | EPHX2 (0.67) | FAAHPDGFRBMAPT | |
| SCHEMBL28363634 | 0.80 | NPC1 (0.65) | FAAHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0958287-B2 | SULFAMIDE-METALLOPROTEASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2008-04-09 | — | — | EP | disclosed |
| EP-0958287-B1 | SULFAMIDE-METALLOPROTEASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2002-09-11 | — | — | EP | disclosed |