Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | FAAH | O00519 | 3/20 | 0.65 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12668376 | 0.92 | SMN1; SMN2 (0.77) | SMN1; SMN2EPHX2KMT2AMEN1ALDH1A1 | |
| SCHEMBL9467061 | 0.87 | MAPT (0.74) | SMN1; SMN2FAAHEPHX2KMT2AMEN1 | |
| SCHEMBL20236423 | 0.87 | FAAH (0.61) | SMN1; SMN2FAAHPDGFRBMAPT | |
| SCHEMBL4676015 | 0.87 | FAAH (0.61) | FAAHPDGFRBMAPT | |
| SCHEMBL4676020 | 0.87 | POLB (0.73) | SMN1; SMN2FAAHPDGFRBMAPT | |
| SCHEMBL22218259 | 0.85 | FAAH (0.60) | SMN1; SMN2FAAHPDGFRBMAPT | |
| SCHEMBL4776281 | 0.85 | CYP2C9 (0.71) | SMN1; SMN2FAAHKMT2AMEN1ALDH1A1 | |
| SCHEMBL28363630 | 0.84 | EPHX2 (0.67) | SMN1; SMN2FAAHEPHX2KMT2AMEN1 | |
| SCHEMBL4051171 | 0.83 | RAB9A (0.69) | SMN1; SMN2KMT2AMEN1ALDH1A1GLA | |
| Hydrochloric Acid SCHEMBL7128759 | 0.83 | POLB (0.72) | SMN1; SMN2FAAHKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110878070-B | Method for preparing asymmetric urea compound | 中国科学院化学研究所 | 2021-08-31 | — | — | CN | disclosed |
| CN-110878070-A | Method for preparing asymmetric urea compound | 中国科学院化学研究所 | 2020-03-13 | — | — | CN | disclosed |
| US-8093246-B2 | potent deoxycytidine kinase inhibitors; O-linked pyrimidin-4-amine-based compounds | LEXICON PHARMACEUTICALS, INC. (US) | 2012-01-10 | — | — | US | disclosed |