Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 6/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3022117 | 0.94 | PDE4B (0.62) | PDE4BTBXAS1SMN1; SMN2TP53 | |
| SCHEMBL3038012 | 0.91 | PDE4B (0.55) | PDE4BHPGDTBXAS1SMN1; SMN2 | |
| SCHEMBL3028542 | 0.91 | PDE4B (0.54) | PDE4BSMN1; SMN2TP53 | |
| SCHEMBL3033040 | 0.90 | PDE4B (0.55) | PDE4BTBXAS1SMN1; SMN2TP53 | |
| SCHEMBL4678948 | 0.89 | PDE4B (0.53) | PDE4BTBXAS1TP53 | |
| SCHEMBL4050522 | 0.89 | PDE4B (0.55) | PDE4BTBXAS1SMN1; SMN2TP53 | |
| SCHEMBL3039960 | 0.89 | PDE4B (0.52) | PDE4BHPGDTBXAS1SMN1; SMN2TP53 | |
| SCHEMBL4053752 | 0.87 | PDE4B (0.49) | PDE4BTBXAS1SMN1; SMN2TP53 | |
| SCHEMBL3033372 | 0.86 | TBXAS1 (0.54) | PDE4BTBXAS1SMN1; SMN2TP53 | |
| SCHEMBL1996275 | 0.85 | PDE4B (0.48) | PDE4BHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575926-B1 | NEW PYRIDAZIN-3(2H)-ONE DERIVATIVES | ALMIRALL LAB (ES) | 2008-03-05 | — | — | EP | claimed |