Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | PDE2A | O00408 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.31 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4675287 | 0.85 | KDM4E (0.36) | KDM4EHKDC1NFE2L2BRAFCYP19A1 | |
| SCHEMBL4675295 | 0.85 | KDM4E (0.36) | KDM4EHKDC1NFE2L2BRAFCYP19A1 | |
| SCHEMBL4671531 | 0.85 | KDM4E (0.36) | KDM4EHKDC1NFE2L2BRAFCYP19A1 | |
| SCHEMBL6721749 | 0.84 | NPSR1 (0.41) | KDM4EHKDC1NFE2L2KAT2BALDH1A1 | |
| SCHEMBL4671613 | 0.84 | NPSR1 (0.41) | KDM4EHKDC1NFE2L2KAT2BALDH1A1 | |
| SCHEMBL4674838 | 0.83 | KDM4E (0.41) | KDM4EHKDC1NFE2L2KAT2BBRAF | |
| SCHEMBL4673211 | 0.83 | KDM4E (0.41) | KDM4EHKDC1NFE2L2KAT2BBRAF | |
| SCHEMBL13417830 | 0.79 | ADORA3 (0.38) | — | |
| SCHEMBL4174183 | 0.75 | GRM5 (0.34) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL2447629 | 0.73 | GRM5 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1375495-B1 | METHOD FOR PRODUCING A 2-AZETIDINONE DERIVATIVE | DAIICHI SANKYO CO LTD (JP) | 2008-09-03 | — | — | EP | disclosed |
| US-7126003-B2 | Method for producing 2-azetidinone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-10-24 | — | — | US | disclosed |
| US-20040072309-A1 | Method for producing 2-azetidinone derivative | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2004-04-15 | — | — | US | disclosed |
| EP-1375495-A1 | METHOD FOR PRODUCING 2-AZETIDINONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2004-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040072309-A1 | Method for producing 2-azetidinone derivative | CYP51A1, AZI2, POR | KDM4E 1139/4885HKDC1 2326/4885NFE2L2 776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.