⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4684074 | 0.84 | — | — | |
| SCHEMBL4680998 | 0.84 | XDH (0.50) | — | |
| SCHEMBL4677409 | 0.83 | — | — | |
| SCHEMBL4680875 | 0.81 | GRK6 (0.53) | — | |
| SCHEMBL4677787 | 0.79 | — | — | |
| SCHEMBL4676520 | 0.77 | MAPT (0.46) | — | |
| SCHEMBL11589338 | 0.76 | — | — | |
| SCHEMBL4680748 | 0.76 | LMNA (0.48) | — | |
| SCHEMBL4680659 | 0.75 | — | — | |
| SCHEMBL4676332 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1471065-B1 | NOVEL 1,2,4-TRIAZOLE COMPOUND | FUJI YAKUHIN CO LTD (JP) | 2008-02-27 | — | — | EP | disclosed |
| US-7074816-B2 | 1 2 4-triazole compound | FUJI YAKUHIN CO., LTD. (JP) | 2006-07-11 | — | — | US | disclosed |
| US-20050004175-A1 | Novel 1 2 4-triazole compound | FUJI YAKUHIN CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| EP-1471065-A1 | NOVEL 1,2,4-TRIAZOLE COMPOUND | Fuji Yakuhin Co., Ltd. (JP) | 2004-10-27 | — | — | EP | disclosed |