Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 3/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14303082 | 0.89 | RORC (0.41) | CHRM1RORCNR3C2BRD4CMA1 | |
| SCHEMBL4677298 | 0.86 | BRD4 (0.37) | NR3C2BRD4CMA1TSHRHTT | |
| SCHEMBL4682695 | 0.84 | CHRM1 (0.34) | CHRM1RORCBRD4POLBTSHR | |
| SCHEMBL900804 | 0.83 | — | — | |
| SCHEMBL4681334 | 0.83 | CHRM1 (0.33) | CHRM1POLB | |
| SCHEMBL30799196 | 0.83 | — | — | |
| SCHEMBL20680726 | 0.83 | — | — | |
| SCHEMBL8593667 | 0.79 | CHRM1 (0.32) | CHRM1RORC | |
| SCHEMBL9598201 | 0.79 | BRD4 (0.35) | CHRM1RORCBRD4CMA1POLB | |
| SCHEMBL8960319 | 0.79 | RORC (0.32) | CHRM1RORCBRD4POLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850227-B1 | PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2008-01-09 | — | — | EP | claimed |
| US-20040005986-A1 | Pyridazin-3-one derivatives, their use, and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-01-08 | — | — | US | claimed |
| US-6482773-B1 | Pyridazin-3-one derivatives, their use, and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-11-19 | — | — | US | claimed |
| EP-0850227-A1 | PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-01 | — | — | EP | claimed |
| WO-1997007104-A1 | PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-02-27 | — | — | WO | claimed |
| EP-0850227-B1 | PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2008-01-09 | — | — | EP | disclosed |
| US-6869913-B1 | Pyridazin-3-one derivatives, their use and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-03-22 | — | — | US | disclosed |
| US-6703503-B2 | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-03-09 | — | — | US | disclosed |
| US-20040005986-A1 | Pyridazin-3-one derivatives, their use, and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-01-08 | — | — | US | disclosed |
| US-6482773-B1 | Pyridazin-3-one derivatives, their use, and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-11-19 | — | — | US | disclosed |
| US-6348628-B1 | HYDRAZONE HERBICIDE INTERMEDIATES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-02-19 | — | — | US | disclosed |
| US-6090753-A | 2-(SUBSTITUTED PHENYL), 5-HALOALKYL-PYRIDAZIN-3-ONE DERIVATIVES AS HERBICIDES; CONTROLLING WEEDS, METHOD OF MAKING BY REACTING A HYDRAZONE DERIVATIVE WITH A SPECIFIED PHOSPHORUS COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2000-07-18 | — | — | US | disclosed |
| EP-0850227-A1 | PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-07-01 | — | — | EP | disclosed |
| WO-1997007104-A1 | PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-02-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040005986-A1 | Pyridazin-3-one derivatives, their use, and intermediates for their production | Q6ZSR9, HDHD5, CBR3 | CHRM1 264/4885RORC 2974/4885NR3C2 3372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.