XPNPEP2 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL17339957	1.00	2/20
SCHEMBL17339958	1.00	2/20
SCHEMBL17339960	0.75	2/20
SCHEMBL17339961	0.74	2/20
SCHEMBL17339959	0.61	2/20
SCHEMBL6679094	0.55	2/20
SCHEMBL6679097	0.55	2/20
SCHEMBL20375838	0.51	2/20
SCHEMBL30069057	0.48	2/20
SCHEMBL14355658	0.45	2/20
SCHEMBL3283616	0.45	2/20
SCHEMBL12233572	0.45	2/20
SCHEMBL6954392	0.43	2/20
SCHEMBL6954395	0.43	2/20
SCHEMBL7068510	0.43	2/20
SCHEMBL12308700	0.40	2/20
SCHEMBL12308668	0.40	2/20
SCHEMBL12308734	0.39	2/20
SCHEMBL31448343	0.48	1/20
SCHEMBL4422194	0.48	1/20

Clinical trials — most relevant to XPNPEP2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
ALL SCTped FORUM - Pharmacogenomic Study (add-on Study)	PHASE4	UNKNOWN
A Study of KRN23 in Pediatric Patients With X-linked Hypophosphatemic Rickets/Osteomalacia	PHASE3	COMPLETED
Improving Outcomes in Neonatal Abstinence Syndrome	PHASE3	COMPLETED
A Study to Evaluate the Safety and Efficacy of Afamelanotide in Patients With Xeroderma Pigmentosum (XP)	PHASE2	UNKNOWN
A Study to Evaluate the Safety, Tolerability and Efficacy of BMN 110 in Subjects With Mucopolysaccharidosis IVA	PHASE1/PHASE2	COMPLETED
Pappalysin 2 (PAPP-A2) Enzyme Replacement	PHASE1	COMPLETED
Calcitonin for Treating X-linked Hypophosphatemia	nan	COMPLETED
The Effect of Monoallelic Variants in the ALPL Gene on the Natural Course of Hypophosphatasia in Russia	nan	RECRUITING
Evaluation of Phenotypic and Genetic Properties in Male Subjects Affected By Hypohidrotic Ectodermal Dysplasia (ECP-012)	nan	COMPLETED
Identifying Genes and Mutations Underlying Retinitis Pigmentosa and Allied Diseases	nan	UNKNOWN
Genetic Studies of Lysosomal Storage Disorders	nan	ENROLLING_BY_INVITATION
Cancer Risk in Carriers of the Gene for Xeroderma Pigmentosum	nan	COMPLETED
Williams Syndrome (WS) and Supravalvar Aortic Stenosis (SVAS) DNA and Tissue Bank	nan	COMPLETED
Genetic Response to Warfarin in Healthy Subjects	nan	COMPLETED
Study of Longitudinal Observation for Patient With X-linked Hypophosphatemic Rickets/Osteomalacia in Collaboration With Asian Partners	nan	ACTIVE_NOT_RECRUITING
X-chromosome Inactivation, Epigenetics and the Transcriptome	nan	COMPLETED
Molecular Associations With Reproductive Failure	nan	COMPLETED
Genome Environment Microbiome and Metabolome in Autism Study	nan	COMPLETED
Developing a Management Approach for Patients With Late-Onset Pompe Disease	nan	ACTIVE_NOT_RECRUITING
Observational Study of Adults and Adolescents With Erythropoietic Protoporphyria (EPP) and X-linked Porphyria (XLP)	nan	RECRUITING
Genetic Investigations in Children With Developmental and Epileptic Encephalopathies in Ho Chi Minh City, Vietnam	nan	UNKNOWN
Genetics of Ehlers-Danlos Syndrome	nan	COMPLETED
Genetic Basis of Abdominal Aortic Aneurysm	nan	COMPLETED
Genetic Characterization of Parkinson's Disease	nan	COMPLETED
Impact of Elastin Mediated Vascular Stiffness on End Organs	nan	COMPLETED
Immune Signature of Palmoplantar Pustulosis	nan	COMPLETED
Role of ADA SNPs in Subjects With Relapsing Multiple Sclerosis (RMS)	nan	UNKNOWN
Modeling DNA Diversity in Reverse Cholesterol Transport	nan	COMPLETED
The Contribution of Optical Mapping to the Characterization of Chromosomal Rearrangements in Patients With Neurodevelopmental Disorders	nan	RECRUITING
InsightRP2 Registry	nan	RECRUITING

Related proteins — ESM-2 sequence neighbours (a XPNPEP2 binder may also engage these)

Protein	Name	Similarity
B1AVD1	—	1.000	B1AVD1 →
Q95333	—	0.998	Q95333 →
Q99MA2	—	0.998	Q99MA2 →
E9EUE6	—	0.982	E9EUE6 →
B0DZL3	—	0.981	B0DZL3 →
E9E9B2	—	0.981	E9E9B2 →
O44750	—	0.980	O44750 →
Q55E60	—	0.979	Q55E60 →
B2AWV6	—	0.979	B2AWV6 →
E3QCU0	—	0.979	E3QCU0 →
Q58DH9	—	0.979	Q58DH9 →
Q2VQV9	—	0.979	Q2VQV9 →
C0NDZ7	—	0.979	C0NDZ7 →
Q08CS6	—	0.978	Q08CS6 →
C6HSY3	—	0.978	C6HSY3 →
MGAM	Maltase-glucoamylase	0.978	landscape →
P28843	—	0.978	P28843 →
C5FHR9	—	0.978	C5FHR9 →
F4JQH3	—	0.978	F4JQH3 →
B8M9W2	—	0.978	B8M9W2 →
A0A2Z5GDY5	—	0.978	A0A2Z5GDY5 →
P51569	—	0.978	P51569 →
A2QGR5	—	0.978	A2QGR5 →
Q5R7P4	—	0.978	Q5R7P4 →
Q9VJG0	—	0.978	Q9VJG0 →
Q8RY11	—	0.977	Q8RY11 →
A1CAQ1	—	0.977	A1CAQ1 →
Q5EA41	—	0.977	Q5EA41 →
E9CTR7	—	0.977	E9CTR7 →
MGAM2	Probable maltase-glucoamylase 2 (Maltase-gluc	0.977	landscape →