Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5A | P29375 | 3/20 | 0.50 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.50 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TARDBP | Q13148 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 2/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4537554 | 0.98 | SIGMAR1 (0.54) | KDM5APHF8KDM2AKDM4CSIGMAR1 | |
| SCHEMBL24095875 | 0.98 | SIGMAR1 (0.54) | KDM5APHF8KDM2AKDM4CSIGMAR1 | |
| SCHEMBL9203 | 0.98 | SIGMAR1 (0.54) | KDM5APHF8KDM2AKDM4CSIGMAR1 | |
| SCHEMBL931403 | 0.98 | SIGMAR1 (0.54) | KDM5APHF8KDM2AKDM4CSIGMAR1 | |
| SCHEMBL11010082 | 0.96 | SIGMAR1 (0.57) | KDM5APHF8KDM2AKDM4CSIGMAR1 | |
| SCHEMBL9718136 | 0.96 | SIGMAR1 (0.57) | KDM5APHF8KDM2AKDM4CSIGMAR1 | |
| SCHEMBL8860844 | 0.96 | SIGMAR1 (0.57) | KDM5APHF8KDM2AKDM4CSIGMAR1 | |
| SCHEMBL13520 | 0.96 | SIGMAR1 (0.57) | KDM5APHF8KDM2AKDM4CSIGMAR1 | |
| SCHEMBL20408333 | 0.96 | SIGMAR1 (0.57) | KDM5APHF8KDM2AKDM4CSIGMAR1 | |
| SCHEMBL19932510 | 0.93 | KDM5A (0.49) | KDM5APHF8KDM2AKDM4CSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1590343-B1 | SYNTHESIS OF 2-BUTYL-3-(2' -(1-TRITYL-1H-TETRAZOL-5-YL)BIPHEN YL-4-YL)-1,3-DIAZASPIRO-4,4 -NONENE-4-ONE | TEVA PHARMA (IL) | 2008-07-16 | — | — | EP | claimed |