Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.54 |
| ▸ | KDM5A | P29375 | 3/20 | 0.51 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.51 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.51 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.51 |
| ▸ | KDM4A | O75164 | 1/20 | 0.51 |
| ▸ | NAAA | Q02083 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TARDBP | Q13148 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9203 | 1.00 | SIGMAR1 (0.54) | SIGMAR1KDM5APHF8KDM2AKDM4C | |
| SCHEMBL8860844 | 0.98 | SIGMAR1 (0.57) | SIGMAR1KDM5APHF8KDM2AKDM4C | |
| SCHEMBL11010082 | 0.98 | SIGMAR1 (0.57) | SIGMAR1KDM5APHF8KDM2AKDM4C | |
| SCHEMBL9718136 | 0.98 | SIGMAR1 (0.57) | SIGMAR1KDM5APHF8KDM2AKDM4C | |
| SCHEMBL20408333 | 0.98 | SIGMAR1 (0.57) | SIGMAR1KDM5APHF8KDM2AKDM4C | |
| SCHEMBL13520 | 0.98 | SIGMAR1 (0.57) | SIGMAR1KDM5APHF8KDM2AKDM4C | |
| SCHEMBL4677733 | 0.98 | KDM5A (0.50) | SIGMAR1KDM5APHF8KDM2AKDM4C | |
| SCHEMBL24095875 | 0.96 | SIGMAR1 (0.54) | SIGMAR1KDM5APHF8KDM2AKDM4C | |
| SCHEMBL4537554 | 0.96 | SIGMAR1 (0.54) | SIGMAR1KDM5APHF8KDM2AKDM4C | |
| SCHEMBL9100 | 0.93 | SIGMAR1 (0.50) | SIGMAR1KDM5APHF8KDM2AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011000945-A2 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-01-06 | — | — | WO | claimed |
| WO-2011000945-A9 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-04-07 | — | — | WO | disclosed |
| WO-2011000945-A2 | AMINOALKAMIDES FOR USE IN THE TREATMENT OF INFLAMMATORY, DEGENERATIVE OR DEMYELINATING DISEASES OF THE CNS | NENSIUS RESEARCH A/S (DK) | 2011-01-06 | — | — | WO | disclosed |