SCHEMBL467889

SCHEMBL467889

C=C[CH]c1ccco1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37113 0.79
Selenium SCHEMBL9160730 0.77
Furfural SCHEMBL11761016 0.76 ALDH1A1 (0.82)
SCHEMBL9454445 0.76
Furfural SCHEMBL2972777 0.75 ALDH1A1 (0.78)
Furfural SCHEMBL5695593 0.73 ALDH1A1 (0.75)
SCHEMBL641747 0.73 ALDH1A1 (0.62)
SCHEMBL490330 0.73 ALDH1A1 (0.62)
SCHEMBL2789580 0.73 ALDH1A1 (0.62)
SCHEMBL19665093 0.71 ALDH1A1 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 798 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6372755-B1 None US claimed
WO-2023217764-A1 NOX INHIBITORS FOR USE IN THE TREATMENT OF ALPORT SYNDROME CALLIDITAS THERAPEUTICS SUISSE SA (CH) 2023-11-16 WO claimed
US-20210177811-A1 USE OF NOX INHIBITORS FOR TREATMENT OF CANCER CALLIDITAS THERAPEUTICS SUISSE SA (CH) 2021-06-17 US claimed
EP-3703747-A1 USE OF NOX INHIBITORS FOR TREATMENT OF CANCER GenKyoTex Suisse SA (CH) 2020-09-09 EP claimed
US-20180170903-A1 PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION VIIV Healthcare UK (No.5) Limited (GB) 2018-06-21 US claimed
EP-3319958-A1 PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION VIIV Healthcare UK (No.5) Limited (GB) 2018-05-16 EP claimed
EP-2356989-B1 STABLE TABLET CONTAINING 4,5-EPOXYMORPHINAN DERIVATIVE TORAY INDUSTRIES (JP) 2018-02-07 EP claimed
EP-1758452-B1 METABOLICALLY STABLE ANALGESICS AND PAIN MEDICATIONS HUMAN BIOMOLECULAR RES INST (US) 2017-01-25 EP claimed
WO-2017006261-A1 PYRIDIN-3-YL ACETIC ACID DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION VIIV Healthcare UK (No.5) Limited (GB) 2017-01-12 WO claimed
CN-105218516-A Therapeutic compounds and related methods of use OTSUKA PHARMA CO LTD 2016-01-06 CN claimed
WO-1987006935-A1 SUBSTITUTED PYRROLES WITH OPIOID RECEPTOR ACTIVITY REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1987-11-19 WO claimed
EP-0244018-A1 Amino-thiazole and oxazole derivatives AKZO N.V. (NL) 1987-11-04 EP claimed
CN-87102879-A Benzhydryl compounds as herbicide antidotes 1987-10-28 CN claimed
CN-85101795-A With 1, the two 2-oxyindoles that replace of 3-prepare pain killer and antiphlogistic 1987-04-08 CN claimed
US-4649200-A Substituted pyrroles with opioid receptor activity REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 1987-03-10 US claimed
CN-85101029-A The method of preparation-2-oxyindole-1-methane amide and intermediate product thereof 1987-01-24 CN claimed
CN-85101028-A Be used as the preparation of 2-oxyindole-1-methane amide that the 3-of anodyne and antiphlogistic replaces 1987-01-17 CN claimed
US-4389410-A Esters of monic acid A useful as antibacterial and antimycoplasmal agents BEECHAM GROUP LIMITED (GB) 1983-06-21 US claimed
US-4260762-A NEUROLEPTICS HOFFMANN-LA ROCHE INC. (US) 1981-04-07 US claimed
US-3951962-A ANTIBACTERIAL YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1976-04-20 US claimed