SCHEMBL490330

SCHEMBL490330

[CH](c1ccco1)c1ccco1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.62
HCAR2 Q8TDS4 1/20 0.48
MAPT P10636 8/20 0.46
KDM4E B2RXH2 2/20 0.46
MAPK1 P28482 2/20 0.46
HPGD P15428 1/20 0.46
HSD17B10 Q99714 1/20 0.46
HSP90AA1 P07900 1/20 0.45
G6PD P11413 1/20 0.45
KMT2A Q03164 7/20 0.45
MEN1 O00255 6/20 0.45
POLB P06746 5/20 0.45
L3MBTL1 Q9Y468 5/20 0.45
GAA P10253 2/20 0.45
HTT P42858 1/20 0.45
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
NPC1 O15118 1/20 0.43
NFKB1 P19838 1/20 0.43
BLM P54132 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL949608 0.82 ALDH1A1 (0.50) ALDH1A1HCAR2MAPTKDM4EMAPK1
SCHEMBL2789580 0.81 ALDH1A1 (0.62) ALDH1A1HCAR2MAPTKDM4EMAPK1
SCHEMBL641747 0.81 ALDH1A1 (0.62) ALDH1A1HCAR2MAPTKDM4EMAPK1
SCHEMBL10617925 0.79
Furfural SCHEMBL10811266 0.77 ALDH1A1 (1.00) ALDH1A1HCAR2MAPTKDM4EMAPK1
SCHEMBL3073828 0.77
SCHEMBL2830604 0.77
SCHEMBL852341 0.77
SCHEMBL9298131 0.77 F2 (0.67) ALDH1A1HCAR2MAPTKDM4EHPGD
SCHEMBL3404813 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117500783-A Perfume compounds 奇华顿股份有限公司 2024-02-02 CN claimed
CN-115806554-A Preparation and application of colon-targeted prodrug and drug delivery system thereof 沈阳海诺威医药科技有限公司 2023-03-17 CN claimed
WO-2022261956-A1 FRAGRANCE COMPOUNDS GIVAUDAN SA (CH) 2022-12-22 WO claimed
CN-108368098-B Microbicidal oxadiazole derivatives 先正达参股股份有限公司 2022-01-28 CN claimed
EP-3774813-A1 PYRAZOLOTRIAZOLOPYRIMIDINE DERIVATIVES AS A2A RECEPTOR ANTAGONIST BeiGene, Ltd. (KY) 2021-02-17 EP claimed
CN-111187262-A Imidazo [1,2-a ] pyridine derivative and preparation method and application thereof 沈阳药科大学 2020-05-22 CN claimed
WO-2019196803-A1 PYRAZOLOTRIAZOLOPYRIMIDINE DERIVATIVES AS A2A RECEPTOR ANTAGONIST BEIGENE, LTD. (KY) 2019-10-17 WO claimed
EP-2121683-A2 2- PIPERAZIN-1-YL-3H-IMIDAZO[4,5-B]PYRIDINE DERIVATIVES Janssen Pharmaceutica, N.V. (BE) 2009-11-25 EP claimed
WO-2008090200-A2 2- PIPERAZIN-1-YL-3H-IMIDAZO[4,5-B]PYRIDINE DERIVATIVES JANSSEN PHARMACEUTICA NV (BE) 2008-07-31 WO claimed
WO-2007028524-A2 USE OF A DERIVATIVE OF IMIDAZOLE FOR THE TREATMENT OF LEUKOTRIENE RELATED DISORDERS PROUS INSTITUTE FOR BIOMEDICAL RESEARCH S.A. (ES) 2007-03-15 WO claimed
WO-2004048348-A1 SUBSTITUTED 2-ARYL-1,2,4-TRIAZINE-3,5-DI(THI) ONES USED AS HERBICIDES BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2004-06-10 WO claimed
CN-1238774-A Pyridobenzoxazine derwatives DAIICHI SEIYAKU CO (JP) 1999-12-15 CN claimed
US-5686459-A ANTICOAGULANTS HOFFMANN-LA ROCHE INC. (US) 1997-11-11 US claimed
WO-2024113351-A1 CULTURE MEDIUM, COATING MATRIX AND METHOD FOR MATURING MIDBRAIN DOPAMINERGIC PROGENITOR CELLS NUWACELL BIOTECHNOLOGIES CO., LTD. (CN) 2024-06-06 WO disclosed
WO-2024113354-A1 CULTURE MEDIUM, COATING MATRIX AND METHOD FOR EXPANDING MIDBRAIN DOPAMINERGIC PROGENITOR CELLS NUWACELL BIOTECHNOLOGIES CO., LTD. (CN) 2024-06-06 WO disclosed
CN-114181883-B Hardness-adjustable hydrogel organoid ball containing matrigel, and preparation method and application thereof 大连大学 2024-04-19 CN disclosed
US-5059597-A Animal growth regulators; enterobacter BAYER AKTIENGESELLSCHAFT (DE) 1991-10-22 US disclosed
US-4990517-A 7-(1-pyrrolidinyl)-3-quinolone- and -naphthyridonecarboxylic acid derivatives as antibacterial agents and feed additives BAYER AKTIENGESELLSCHAFT (DE) 1991-02-05 US disclosed
US-4888426-A CHEMICAL INTERMEDIATES JANSSEN PHARMACEUTICA N.V. (BE) 1989-12-19 US disclosed
US-4415566-A ANTIBIOTICS; BACTERIOSTATS; BACTERICIDES BOEHRINGER INGELHEIM GMBH (DE) 1983-11-15 US disclosed