Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3635237 | 0.81 | TSHR (0.54) | TSHRALDH1A1SIGMAR1SLC6A2SLC6A3 | |
| SCHEMBL10386656 | 0.80 | ADRA2B (0.62) | TSHRALDH1A1SIGMAR1SLC6A2SLC6A3 | |
| SCHEMBL8114380 | 0.77 | TSHR (0.50) | TSHRALDH1A1SIGMAR1SLC6A2SLC6A3 | |
| SCHEMBL1593286 | 0.77 | TSHR (0.50) | TSHRALDH1A1SIGMAR1SLC6A2SLC6A3 | |
| SCHEMBL10653713 | 0.77 | TSHR (0.50) | TSHRALDH1A1SIGMAR1SLC6A2SLC6A3 | |
| SCHEMBL10653246 | 0.77 | TSHR (0.50) | TSHRALDH1A1SIGMAR1SLC6A2SLC6A3 | |
| SCHEMBL15233943 | 0.77 | TSHR (0.50) | TSHRALDH1A1SIGMAR1SLC6A2SLC6A3 | |
| SCHEMBL18079513 | 0.77 | TSHR (0.50) | TSHRALDH1A1SIGMAR1SLC6A2SLC6A3 | |
| SCHEMBL11291918 | 0.77 | SLC6A2 (0.52) | TSHRALDH1A1SIGMAR1SLC6A2SLC6A3 | |
| SCHEMBL8864186 | 0.77 | TSHR (0.45) | TSHRALDH1A1SIGMAR1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101742909-A | Have purposes and weed killer herbicide and the algaecide composition of the compound of single galactosyl DG synthase inhibitory activity as weed killer herbicide or algicide | CENTRE NAT RECH SCIENT | 2010-06-16 | — | — | CN | claimed |
| CN-101742909-B | Use of compounds having a monogalactosyldiacylglycerol synthase inhibitory activity as herbicide or algaecide, herbicide and algaecide compositions | COMMISSARIAT ENERGIE ATOMIQUE | 2014-07-09 | — | — | CN | disclosed |
| CN-101742909-A | Have purposes and weed killer herbicide and the algaecide composition of the compound of single galactosyl DG synthase inhibitory activity as weed killer herbicide or algicide | CENTRE NAT RECH SCIENT | 2010-06-16 | — | — | CN | disclosed |
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | disclosed |