Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 2/20 | 0.47 |
| ▸ | CCR5 | P51681 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.37 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4679688 | 1.00 | FPR2 (0.47) | FPR2CCR5LMNASMN1; SMN2TSHR | |
| SCHEMBL3745057 | 0.88 | LMNA (0.53) | FPR2CCR5LMNASMN1; SMN2TSHR | |
| SCHEMBL3745050 | 0.88 | LMNA (0.53) | FPR2CCR5LMNASMN1; SMN2TSHR | |
| SCHEMBL3742103 | 0.87 | LMNA (0.41) | FPR2CCR5LMNASMN1; SMN2TSHR | |
| SCHEMBL3742093 | 0.87 | LMNA (0.41) | FPR2CCR5LMNASMN1; SMN2TSHR | |
| SCHEMBL3751317 | 0.86 | BRD4 (0.48) | FPR2CCR5LMNASMN1; SMN2TSHR | |
| SCHEMBL3751321 | 0.86 | BRD4 (0.48) | FPR2CCR5LMNASMN1; SMN2TSHR | |
| SCHEMBL4801360 | 0.83 | FPR2 (0.37) | FPR2CCR5SMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL4678005 | 0.80 | FPR2 (0.43) | FPR2CCR5LMNAMAPTMEN1 | |
| SCHEMBL4678008 | 0.80 | FPR2 (0.43) | FPR2CCR5LMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | disclosed |