Taxiphyllin

Taxiphyllin

SCHEMBL467975

N#CC(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)c1ccc(O)cc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TYR P14679 7/20 0.56
PPARG P37231 2/20 0.51
PPARD Q03181 2/20 0.51
PPARA Q07869 2/20 0.51
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
G6PD P11413 1/20 0.46
MAPK1 P28482 1/20 0.46
ADRA1A P35348 1/20 0.46
PTGS2 P35354 1/20 0.46
SLC28A3 Q9HAS3 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Taxiphyllin SCHEMBL50174 1.00 TYR (0.56) TYRPPARGPPARDPPARAMAPT
Taxiphyllin SCHEMBL1332701 1.00 TYR (0.56) TYRPPARGPPARDPPARAMAPT
Taxiphyllin SCHEMBL12727838 1.00 TYR (0.56) TYRPPARGPPARDPPARAMAPT
Prunasin SCHEMBL4925774 0.88 SYNJ2 (0.50) TYRMAPTKDM4EPOLBGAA
Prunasin SCHEMBL30671478 0.88 SYNJ2 (0.50) TYRMAPTKDM4EPOLBGAA
Prunasin SCHEMBL16147925 0.88 SYNJ2 (0.50) TYRMAPTKDM4EPOLBGAA
Prunasin SCHEMBL440675 0.88 SYNJ2 (0.50) TYRMAPTKDM4EPOLBGAA
Prunasin SCHEMBL377612 0.88 SYNJ2 (0.50) TYRMAPTKDM4EPOLBGAA
SCHEMBL29649717 0.88 TYR (0.60) TYRPOLB
SCHEMBL30592415 0.85 TYR (0.47) TYRPPARGPPARDPPARAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1649029-B1 A METHOD OF PRODUCING A LOW MOLECULAR WEIGHT PLANT SECONDARY METABOLITE IN A YEAST CELL EVOLVA SA (CH) 2014-12-17 EP disclosed
EP-2388333-A2 A method of producing a low molecular weight organic compound in a cell Evolva SA (CH) 2011-11-23 EP disclosed
US-8041750-B2 Method and apparatus for organizing and playing data YAHOO! INC. (US) 2011-10-18 US disclosed
US-7846697-B2 Method of producing a low molecular weight organic compound in a cell BLMaps (DK) 2010-12-07 US disclosed
US-20060275877-A1 Method of producing a low molecular weight organic compound in a cell DANSTAR FERMENT AG (CH) 2006-12-07 US disclosed