Taxiphyllin

Taxiphyllin

SCHEMBL50174

N#C[C@@H](O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)c1ccc(O)cc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TYR P14679 7/20 0.56
PPARG P37231 2/20 0.51
PPARD Q03181 2/20 0.51
PPARA Q07869 2/20 0.51
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
G6PD P11413 1/20 0.46
MAPK1 P28482 1/20 0.46
ADRA1A P35348 1/20 0.46
PTGS2 P35354 1/20 0.46
SLC28A3 Q9HAS3 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Taxiphyllin SCHEMBL1332701 1.00 TYR (0.56) TYRPPARGPPARDPPARAMAPT
Taxiphyllin SCHEMBL467975 1.00 TYR (0.56) TYRPPARGPPARDPPARAMAPT
Taxiphyllin SCHEMBL12727838 1.00 TYR (0.56) TYRPPARGPPARDPPARAMAPT
Prunasin SCHEMBL4925774 0.88 SYNJ2 (0.50) TYRMAPTKDM4EPOLBGAA
Prunasin SCHEMBL30671478 0.88 SYNJ2 (0.50) TYRMAPTKDM4EPOLBGAA
Prunasin SCHEMBL16147925 0.88 SYNJ2 (0.50) TYRMAPTKDM4EPOLBGAA
Prunasin SCHEMBL440675 0.88 SYNJ2 (0.50) TYRMAPTKDM4EPOLBGAA
Prunasin SCHEMBL377612 0.88 SYNJ2 (0.50) TYRMAPTKDM4EPOLBGAA
SCHEMBL29649717 0.88 TYR (0.60) TYRPOLB
SCHEMBL30592415 0.85 TYR (0.47) TYRPPARGPPARDPPARAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 424 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260132413-A1 AROGENATE DEHYDROGENASE POLYNUCLEOTIDES, POLYPEPTIDES AND METHODS OF USING THE SAME WISCONSIN ALUMNI RES FOUNDATION (US) 2026-05-14 US claimed
EP-4649136-A1 GENETIC MODIFICATION OF MICROBES FOR PRODUCTION OF NITROGEN AND CARBON-CONTAINING COMPOUNDS Fertis India Pvt Ltd (IN) 2025-11-19 EP claimed
EP-4594520-A2 COMPOSITIONS CONTAINING OLIGONUCLEOTIDES WITH THERANOSTIC APPLICATIONS Sixfold Bioscience Ltd. (GB) 2025-08-06 EP claimed
US-20250136952-A1 ENGINEERED PREPHENATE DEHYDROGENASES AND AROGENATE DEHYDROGENASES AND METHODS OF USING THE SAME WISCONSIN ALUMNI RESEARCH FOUNDATION 2025-05-01 US claimed
US-12134788-B2 Engineered prephenate dehydrogenases and arogenate dehydrogenases and methods of using the same WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2024-11-05 US claimed
WO-2024121871-A1 GENETIC MODIFICATION OF MICROBES FOR PRODUCTION OF NITROGEN AND CARBON-CONTAINING COMPOUNDS FERTIS INDIA PVT. LTD. (IN) 2024-06-13 WO claimed
WO-2024069235-A2 COMPOSITIONS CONTAINING OLIGONUCLEOTIDES WITH THERANOSTIC APPLICATIONS Sixfold Bioscience Ltd. (GB) 2024-04-04 WO claimed
WO-2022187816-A1 GENETIC PURITY ESTIMATE METHOD BY SEQUENCING INDIANA CROP IMPROVEMENT ASSOCIATION (US) 2022-09-09 WO claimed
US-20220282339-A1 GENETIC PURITY ESTIMATE METHOD BY SEQUENCING INDIANA CROP IMPROVEMENT ASSOCIATION 2022-09-08 US claimed
US-20210395701-A1 ENGINEERED PREPHENATE DEHYDROGENASES AND AROGENATE DEHYDROGENASES AND METHODS OF USING THE SAME WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2021-12-23 US claimed
CN-103597071-A Chemosensory receptor ligand-based therapies ELCELYX THERAPEUTICS INC 2014-02-19 CN claimed
EP-2661266-A2 CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES Elcelyx Therapeutics, Inc. (US) 2013-11-13 EP claimed
WO-2012170727-A1 FLUOROGENIC SEMICONDUCTOR NANOCRYSTALS Life Technologies Corporation (US) 2012-12-13 WO claimed
WO-2012126059-A1 NOVEL STOCK FEED CROP PLANT MONASH UNIVERSITY (AU) 2012-09-27 WO claimed
EP-2486404-A1 METABOLIC BIOMARKERS OF DRUG-INDUCED CARDIOTOXICITY Wisconsin Alumni Research Foundation (US) 2012-08-15 EP claimed
WO-2012094636-A2 CHEMOSENSORY RECEPTOR LIGAND-BASED THERAPIES ELCELYX THERAPEUTICS, INC. (US) 2012-07-12 WO claimed
WO-2011044253-A1 METABOLIC BIOMARKERS OF DRUG-INDUCED CARDIOTOXICITY WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2011-04-14 WO claimed
US-20110081675-A1 Metabolic Biomarkers Of Drug-Induced Cardiotoxicity WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2011-04-07 US claimed
US-7122657-B2 UDP-glucose aglycon-glucosytransferase MOLLER, BIRGER LINDBERG (DK) 2006-10-17 US claimed
US-20050277766-A1 Udp-glucose aglycon-glucosytransferase MOLLER, BIRGER LINDBERG (DK) 2005-12-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132413-A1 AROGENATE DEHYDROGENASE POLYNUCLEOTIDES, POLYPEPTIDES AND METHODS OF USING THE SAME PNP, RNGTT, DPYD TYR 527/4885PPARG 2942/4885PPARD 1234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.