Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.43 |
| ▸ | CCND1 | P24385 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4679118 | 0.95 | CDK4 (0.43) | CDK4CCND1MAPTRAB9ANPC1 | |
| SCHEMBL5222966 | 0.90 | KDM4E (0.39) | CDK4CCND1MAPTRAB9ANPC1 | |
| SCHEMBL21177597 | 0.85 | POLB (0.48) | MAPTPOLBLMNANPSR1HSD17B10 | |
| SCHEMBL4707506 | 0.82 | MAPT (0.51) | CDK4CCND1MAPTPOLBLMNA | |
| SCHEMBL4682844 | 0.80 | MAPT (0.50) | MAPTRAB9ANPC1POLBLMNA | |
| SCHEMBL4679798 | 0.80 | CYP2C8 (0.46) | CDK4CCND1POLBLMNAHPGD | |
| SCHEMBL4676503 | 0.79 | CDC25B (0.55) | MAPTRAB9ANPC1POLBLMNA | |
| SCHEMBL21179414 | 0.78 | MAPT (0.46) | MAPTPOLBLMNANPSR1HSD17B10 | |
| SCHEMBL4703665 | 0.77 | MAPT (0.51) | CDK4CCND1MAPTPOLBLMNA | |
| SCHEMBL4675274 | 0.76 | CDC25B (0.55) | MAPTRAB9ANPC1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572672-B1 | BENZOXAZOCINES AND THEIR USE AS MONOAMINE-REUPTAKE INHIBITORS | SOSEI R & D LTD (GB) | 2008-08-13 | — | — | EP | disclosed |
| EP-1950206-A1 | Benzoxazocines and their use as monoamine-reuptake inhibitors | Sosei R&D Ltd. (GB) | 2008-07-30 | — | — | EP | disclosed |
| US-20060019940-A1 | Novel benzoxazocines and their therapeutic use | SOSEI R&D LTD. (GB) | 2006-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060019940-A1 | Novel benzoxazocines and their therapeutic use | HTR4, OPRM1, GRM4 | CDK4 352/4885CCND1 546/4885MAPT 3319/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.