Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10416874 | 0.85 | RORC (0.45) | RORCCSNK2A1BRD4KCNQ3KCNQ2 | |
| Hydrochloric Acid SCHEMBL4679390 | 0.83 | RORC (0.44) | RORCCSNK2A1BRD4KCNQ3KCNQ2 | |
| SCHEMBL7529718 | 0.83 | MEN1 (0.34) | RORCMEN1KMT2A | |
| SCHEMBL7972825 | 0.81 | GRM4 (0.46) | GRM4HDAC6EGFRMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4684813 | 0.79 | RORC (0.34) | RORCCSNK2A1GRM4POLBP2RX3 | |
| SCHEMBL6497946 | 0.76 | CYP2D6 (0.39) | EGFRALDH1A1P2RX3 | |
| SCHEMBL30623235 | 0.74 | RORC (0.78) | RORCGRM4HDAC6ALDH1A1MAPT | |
| SCHEMBL17603152 | 0.74 | RORC (0.78) | RORCGRM4HDAC6ALDH1A1MAPT | |
| SCHEMBL9664574 | 0.74 | CYP17A1 (0.34) | GRM4HDAC6MEN1KMT2AKDM4E | |
| SCHEMBL13715960 | 0.73 | CSNK2A1 (0.43) | RORCCSNK2A1ALDH1A1LMNATRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0850227-B1 | PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL CO (JP) | 2008-01-09 | — | — | EP | disclosed |
| US-6869913-B1 | Pyridazin-3-one derivatives, their use and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-03-22 | — | — | US | disclosed |
| US-6703503-B2 | HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-03-09 | — | — | US | disclosed |
| US-20040005986-A1 | Pyridazin-3-one derivatives, their use, and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-01-08 | — | — | US | disclosed |
| US-6482773-B1 | Pyridazin-3-one derivatives, their use, and intermediates for their production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-11-19 | — | — | US | disclosed |
| EP-0934255-B1 | PRODUCTION OF PYRIDAZINE HERBICIDES | SUMITOMO CHEMICAL CO (JP) | 2002-07-31 | — | — | EP | disclosed |
| EP-0934254-B1 | PRODUCTION OF PYRIDAZINE HERBICIDES | SUMITOMO CHEMICAL CO (JP) | 2002-04-17 | — | — | EP | disclosed |
| US-6348628-B1 | HYDRAZONE HERBICIDE INTERMEDIATES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-02-19 | — | — | US | disclosed |
| US-6333413-B1 | PYRIDAZIN-3-ONE DERIVATIVES BY CYCLIZING THE CARBOXY-SUBSTITUTED HYDRAZONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-12-25 | — | — | US | disclosed |
| US-6218338-B1 | FOR WEEDING BY FOLIAR TREATMENT IN CORN OR SOYABEAN FIELDS | SUMITOMO CHEMICAL CO., LTD (JP) | 2001-04-17 | — | — | US | disclosed |
| WO-1998017632-A1 | PRODUCTION OF PYRIDAZINE HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-04-30 | — | — | WO | disclosed |
| WO-1998017633-A1 | PRODUCTION OF PYRIDAZINE HERBICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-04-30 | — | — | WO | disclosed |
| WO-1997007104-A1 | PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-02-27 | — | — | WO | disclosed |
| US-4906284-A | Herbicidal fluoropropyl compounds | FMC CORPORATION (US) | 1990-03-06 | — | — | US | disclosed |
| US-4842640-A | HIGH ACTIVITY; RICE | RHONE-POULENC AGROCHIMIE (FR) | 1989-06-27 | — | — | US | disclosed |
| US-4835286-A | 2-Substituted phenyl-4,5,6,7-tetrahydro-2H-indazoles | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-05-30 | — | — | US | disclosed |
| EP-0274249-A1 | Oxadiazolone derivative, production process thereof, and herbicide containing same | RHONE-POULENC AGROCHIMIE (FR) | 1988-07-13 | — | — | EP | disclosed |
| WO-1988004653-A1 | OXADIAZOLONE DERIVATIVE, PRODUCTION PROCESS THEREOF, AND HERBICIDE CONTAINING SAME | SHOWA RHODIA CHEMICALS KABUSHIKI KAISHA (JP) | 1988-06-30 | — | — | WO | disclosed |
| US-4670043-A | Herbicidal 2-substituted phenyl-4,5,6,7-tetrahydro-2H-indazoles | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-06-02 | — | — | US | disclosed |
| EP-0105721-A2 | 2-Substituted phenyl-4,5,6,7-tetrahydro-2H-indazoles, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-04-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040005986-A1 | Pyridazin-3-one derivatives, their use, and intermediates for their production | Q6ZSR9, HDHD5, CBR3 | RORC 2974/4885CSNK2A1 3546/4885BRD4 496/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.