Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.39 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 3/20 | 0.37 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.36 |
| ▸ | TEAD4 | Q15561 | 2/20 | 0.36 |
| ▸ | TEAD2 | Q15562 | 2/20 | 0.36 |
| ▸ | TEAD3 | Q99594 | 2/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DAGLB | Q8NCG7 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4682706 | 0.82 | PTGER4 (0.48) | PTGDR2TP53GCGRPTGER4GIPR | |
| SCHEMBL4682121 | 0.78 | KDM5A (0.38) | PTGDR2TP53KDM5AKDM2BKDM4C | |
| SCHEMBL4681192 | 0.74 | TRPM2 (0.41) | PTGDR2KDM2BKDM4CPTGER4 | |
| SCHEMBL4679879 | 0.71 | MAPT (0.53) | SLC5A1SLC5A2DAGLAGCGRMAPT | |
| SCHEMBL4682043 | 0.70 | PTGER4 (0.50) | PTGDR2TP53PTGER4 | |
| SCHEMBL4683639 | 0.69 | GRK6 (0.45) | KDM5AKDM2BKDM4CKDM5BPTGER4 | |
| SCHEMBL4677624 | 0.68 | GCGR (0.41) | KDM5AKDM2BKDM4CKDM5BDAGLA | |
| SCHEMBL4685142 | 0.68 | SCN9A (0.42) | PTGDR2KDM2BKDM4CMAPT | |
| SCHEMBL4682097 | 0.68 | PTGDR2 (0.51) | PTGDR2PTGER4 | |
| SCHEMBL5418558 | 0.66 | MAPT (0.40) | DAGLAGCGRMAPTGIPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513796-B1 | PHENYLOXYALKANOIC ACID DERIVATIVES AS HPPAR ACTIVATORS | SMITHKLINE BEECHAM CORP (US) | 2008-02-13 | — | — | EP | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |
| US-20050222424-A1 | Phenyloxyalkanonic acid derivatives as hppar activators | SMITHKLINE BEECHAM CORPORATION | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222424-A1 | Phenyloxyalkanonic acid derivatives as hppar activators | CEL, HPN, LIPA | PTGDR2 494/4885TP53 1707/4885SLC5A1 105/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.