Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 7/20 | 0.65 |
| ▸ | CTSK | P43235 | 11/20 | 0.62 |
| ▸ | CTSB | P07858 | 4/20 | 0.61 |
| ▸ | CTSS | P25774 | 4/20 | 0.61 |
| ▸ | CTSV | O60911 | 1/20 | 0.60 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154920 | 1.00 | CTSL (0.65) | CTSLCTSKCTSBCTSSCTSV | |
| SCHEMBL2157177 | 0.92 | CTSL (0.64) | CTSLCTSKCTSBCTSSCTSV | |
| SCHEMBL2154927 | 0.90 | CTSL (0.64) | CTSLCTSKCTSBCTSSCTSV | |
| SCHEMBL2156876 | 0.89 | CTSL (0.79) | CTSLCTSKCTSBCTSSCTSV | |
| SCHEMBL2155919 | 0.89 | CTSL (0.68) | CTSLCTSKCTSBCTSSCTSV | |
| SCHEMBL2157024 | 0.89 | CTSL (0.67) | CTSLCTSKCTSBCTSSCTSV | |
| SCHEMBL2155782 | 0.89 | CTSL (0.67) | CTSLCTSKCTSBCTSSCTSV | |
| SCHEMBL2156275 | 0.89 | CTSK (0.69) | CTSLCTSKCTSBCTSSCTSV | |
| SCHEMBL2156033 | 0.88 | CTSL (0.66) | CTSLCTSKCTSBCTSSCTSV | |
| SCHEMBL12396647 | 0.87 | CTSL (0.61) | CTSLCTSKCTSBCTSSCTSV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1482924-B1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK FROSST CANADA LTD (CA) | 2008-05-21 | — | — | EP | claimed |