SCHEMBL468013

SCHEMBL468013

COC(=O)Cc1ccccc1OC

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
TSHR P16473 2/20 0.58
MAPT P10636 1/20 0.58
TAAR1 Q96RJ0 1/20 0.56
MTNR1A P48039 1/20 0.56
MTNR1B P49286 1/20 0.56
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
GAA P10253 2/20 0.55
ATM Q13315 1/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
TDP1 Q9NUW8 1/20 0.55
ALDH1A1 P00352 2/20 0.55
LMNA P02545 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
HPGD P15428 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30027909 1.00 MEN1 (0.58) MEN1KMT2ATSHRMAPTTAAR1
SCHEMBL4059781 0.89 L3MBTL1 (0.55) MEN1KMT2ATSHRMAPTTAAR1
SCHEMBL1554320 0.86 KDM4E (0.53) TSHRMAPTL3MBTL1TDP1ALDH1A1
SCHEMBL6554270 0.85 KDM4E (0.44) MEN1KMT2ATSHRMAPTTAAR1
SCHEMBL28448312 0.85 KDM4E (0.44) MEN1KMT2ATSHRMAPTTAAR1
SCHEMBL2090857 0.85 KDM4E (0.44) MEN1KMT2ATSHRMAPTTAAR1
SCHEMBL10903457 0.85 L3MBTL1 (0.52) MEN1KMT2ATSHRMAPTTAAR1
SCHEMBL27283396 0.85 L3MBTL1 (0.52) MEN1KMT2ATSHRMAPTTAAR1
SCHEMBL28118170 0.84 ATM (0.58) MEN1KMT2ATSHRMAPTTAAR1
SCHEMBL4646605 0.84 KDM4E (0.47) MEN1KMT2ATSHRMAPTTAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 302 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109096425-A A kind of catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2018-12-28 CN claimed
CN-108929226-A A method of preparing benzoyl formic acid ester derivant 广东工业大学 2018-12-04 CN claimed
CN-108440299-A A method of preparing 4- nitro benzophenone class compounds 长沙理工大学 2018-08-24 CN claimed
WO-2025122979-A1 COMPOUNDS FOR SEROTONIN RECEPTOR ACTIVATION AND PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING THE SAME ATAI THERAPEUTICS, INC. (US) 2025-06-12 WO disclosed
US-20250051344-A1 BIFUNCTIONAL SELECTIVE DEGRADERS OF SMARCA2 AND THERAPEUTIC USES THEREOF NURIX THERAPEUTICS, INC. 2025-02-13 US disclosed
US-12152023-B2 Compositions, formulations and methods for treating ocular diseases EyePoint Pharmaceuticals, Inc. (US) 2024-11-26 US disclosed
US-20240368151-A1 NOVEL ERGOLINES AND METHODS OF TREATING MOOD DISORDERS GILGAMESH PHARMACEUTICALS, INC. (US) 2024-11-07 US disclosed
US-20240245658-A1 TAAR1 AND SEROTONIN MODULATORS, AND PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF SUNOVION PHARMACEUTICALS INC. 2024-07-25 US disclosed
WO-2024091506-A2 NOVEL ERGOLINES AND METHODS OF TREATING MOOD DISORDERS GILGAMESH PHARMACEUTICALS, INC. (US) 2024-05-02 WO disclosed
CN-117945973-A Trifluoromethyl sulfoxide reagent and preparation method and application thereof 西北大学 2024-04-30 CN disclosed
CN-117677618-A Novel ergoline and method for treating mood disorders 吉尔伽美什制药公司 2024-03-08 CN disclosed
US-5172704-A SMOKING COMPOSITIONS CONTAINING A VANILLIN-RELEASE ADDITIVE PHILIP MORRIS INCORPORATED (US) 1992-12-22 US disclosed
EP-0510817-A1 Smoking compositions containing a vanillin-release additive Philip Morris Products Inc. (US) 1992-10-28 EP disclosed
US-5063225-A Antiarrhythmia ROUSSEL UCLAF (FR) 1991-11-05 US disclosed
CN-1045777-A Alpha-substitution-preparation method of 4-(quinoline-2-base-methoxyl group) toluylic acid and ester BAYER AG (DE) 1990-10-03 CN disclosed
EP-0150166-B1 NOVEL ARYLACITIC ACID DERIVATIVES PHARMACIA AB (SE) 1988-07-20 EP disclosed
US-4695648-A PROSTAGLANDIN DEHYDROGENASE INHIBITORS PHARMACIA AB (SE) 1987-09-22 US disclosed
EP-0168467-A1 NOVEL ARYLACETIC ACID DERIVATIVES PHARMACIA AB (SE) 1986-01-22 EP disclosed
WO-1985003287-A1 NOVEL ARYLACETIC ACID DERIVATIVES PHARMACIA AB (SE) 1985-08-01 WO disclosed
EP-0150166-A1 Novel arylacitic acid derivatives PHARMACIA AB (SE) 1985-07-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240245658-A1 TAAR1 AND SEROTONIN MODULATORS, AND PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF TAAR1, TAAR5, NPY1R MEN1 934/4885KMT2A 3544/4885TSHR 58/4885
US-20240368151-A1 NOVEL ERGOLINES AND METHODS OF TREATING MOOD DISORDERS HTR2C, GRIN2C, ERG MEN1 1273/4885KMT2A 346/4885TSHR 2356/4885
US-12152023-B2 Compositions, formulations and methods for treating ocular diseases TIE1, TEK, KDR MEN1 875/4885KMT2A 1502/4885TSHR 2208/4885
US-20250051344-A1 BIFUNCTIONAL SELECTIVE DEGRADERS OF SMARCA2 AND THERAPEUTIC USES THEREOF SMARCA2, SMARCE1, SMARCB1 MEN1 1844/4885KMT2A 217/4885TSHR 3787/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.