Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPE | Q05469 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 15/20 | 0.45 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4684875 | 0.92 | CNR1 (0.45) | LIPECNR1CNR2ALDH1A1 | |
| SCHEMBL4684331 | 0.85 | LIPE (0.54) | LIPECNR1CNR2 | |
| SCHEMBL4680276 | 0.85 | CNR1 (0.52) | CNR1CNR2ALDH1A1 | |
| SCHEMBL4680846 | 0.84 | LIPE (0.48) | LIPECNR1CNR2 | |
| SCHEMBL4681228 | 0.82 | LIPE (0.43) | LIPECNR1CNR2 | |
| SCHEMBL4684182 | 0.81 | LIPE (0.46) | LIPECNR1CNR2 | |
| SCHEMBL4684381 | 0.81 | LIPE (0.50) | LIPECNR1CNR2ALDH1A1 | |
| SCHEMBL4680618 | 0.81 | LIPE (0.45) | LIPECNR1CNR2 | |
| SCHEMBL4679631 | 0.80 | LIPE (0.47) | LIPECNR1CNR2 | |
| SCHEMBL4677885 | 0.80 | LIPE (0.47) | LIPECNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638953-B1 | 3-SUBSTITUTED 5,6-DIARYL-PYRAZINE-2-CARBOXAMIDE AND -2-SULFONAMIDE DERIVATIVES AS CB1 MODULATORS | ASTRAZENECA AB (SE) | 2008-08-27 | — | — | EP | claimed |