Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4679583 | 1.00 | USP2 (0.39) | USP2GAAITGB3ITGAVHSD17B10 | |
| SCHEMBL8326662 | 0.93 | USP2 (0.37) | USP2GAAITGB3ITGAVHSD17B10 | |
| SCHEMBL4680620 | 0.93 | ITGB3 (0.43) | USP2GAAITGB3ITGAVHSD17B10 | |
| SCHEMBL4853017 | 0.93 | ITGB3 (0.43) | USP2GAAITGB3ITGAVHSD17B10 | |
| SCHEMBL4852776 | 0.93 | ITGB3 (0.43) | USP2GAAITGB3ITGAVHSD17B10 | |
| SCHEMBL4685497 | 0.92 | USP2 (0.37) | USP2GAAITGB3ITGAVHSD17B10 | |
| SCHEMBL4683912 | 0.91 | IDO1 (0.40) | USP2GAAITGB3HSD17B10ALOX15 | |
| SCHEMBL8330384 | 0.91 | IDO1 (0.40) | USP2GAAITGB3HSD17B10ALOX15 | |
| SCHEMBL4682248 | 0.85 | ITGB3 (0.36) | USP2GAAITGB3ITGAVHSD17B10 | |
| SCHEMBL14143519 | 0.85 | ITGB3 (0.36) | USP2GAAITGB3ITGAVHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594853-B1 | METHOD FOR THE PRODUCTION OF BICYCLIC AROMATIC AMINO ACIDS AND INTERMEDIATE PRODUCTS THEREOF | MERCK PATENT GMBH (DE) | 2008-07-09 | — | — | EP | claimed |
| EP-1594853-B1 | METHOD FOR THE PRODUCTION OF BICYCLIC AROMATIC AMINO ACIDS AND INTERMEDIATE PRODUCTS THEREOF | MERCK PATENT GMBH (DE) | 2008-07-09 | — | — | EP | disclosed |
| US-7371854-B2 | Method for the production of bicyclic aromatic amino acids and intermediate products thereof | MERCK PATENT GMBH (DE) | 2008-05-13 | — | — | US | disclosed |
| US-7371854-B2 | Method for the production of bicyclic aromatic amino acids and intermediate products thereof | MERCK PATENT GMBH (DE) | 2008-05-13 | — | — | US | disclosed |