Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1261383 | 0.73 | ALDH1A1 (0.54) | ALDH1A1HSD17B10 | |
| SCHEMBL295035 | 0.72 | CYP1A2 (0.54) | — | |
| SCHEMBL530121 | 0.71 | KMT2A (0.37) | ALDH1A1 | |
| SCHEMBL2478096 | 0.71 | — | — | |
| SCHEMBL1500175 | 0.70 | NCF1 (0.38) | — | |
| SCHEMBL27824785 | 0.68 | — | — | |
| SCHEMBL6231133 | 0.68 | MGAM (0.38) | ALDH1A1 | |
| SCHEMBL18109831 | 0.68 | BACE1 (0.50) | ALDH1A1 | |
| SCHEMBL16655123 | 0.67 | PARP1 (0.33) | — | |
| SCHEMBL2476823 | 0.67 | BACE1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1416933-B8 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEN INC (US) | 2008-08-27 | — | — | EP | disclosed |
| EP-1416933-A1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | Amgem, Inc. (US) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003009847-A1 | SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR | AMGEM, INC. (US) | 2003-02-06 | — | — | WO | disclosed |