Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 4/20 | 0.44 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3669342 | 0.90 | CACNA1G (0.53) | CACNA1GCACNA1HCYP2D6OPRM1TACR1 | |
| SCHEMBL3741812 | 0.90 | CACNA1G (0.53) | CACNA1GCACNA1HCYP2D6OPRM1TACR1 | |
| SCHEMBL3752377 | 0.89 | SMN1; SMN2 (0.40) | CACNA1GCACNA1HCYP2D6CYP3A4SMN1; SMN2 | |
| SCHEMBL3635264 | 0.89 | SMN1; SMN2 (0.40) | CACNA1GCACNA1HCYP2D6CYP3A4SMN1; SMN2 | |
| SCHEMBL3741872 | 0.84 | ALDH1A1 (0.39) | CACNA1GCACNA1HCYP2D6SMN1; SMN2 | |
| SCHEMBL3632017 | 0.84 | ALDH1A1 (0.39) | CACNA1GCACNA1HCYP2D6SMN1; SMN2 | |
| SCHEMBL3753916 | 0.84 | ALDH1A1 (0.45) | CYP2D6CYP3A4SMN1; SMN2 | |
| SCHEMBL3753910 | 0.84 | ALDH1A1 (0.45) | CYP2D6CYP3A4SMN1; SMN2 | |
| SCHEMBL3747348 | 0.83 | SMN1; SMN2 (0.39) | CACNA1GCACNA1HSMN1; SMN2 | |
| SCHEMBL3634034 | 0.83 | SMN1; SMN2 (0.39) | CACNA1GCACNA1HSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | claimed |