Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.43 |
| ▸ | PPARD | Q03181 | 15/20 | 0.43 |
| ▸ | PPARG | P37231 | 12/20 | 0.43 |
| ▸ | FBP1 | P09467 | 1/20 | 0.37 |
| ▸ | AGER | Q15109 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4679123 | 0.91 | PPARA (0.45) | PPARAPPARDPPARGFBP1GPR119 | |
| SCHEMBL4677889 | 0.83 | FBP1 (0.40) | PPARAPPARDPPARGFBP1AGER | |
| SCHEMBL4679444 | 0.81 | FBP1 (0.38) | PPARAPPARDPPARGFBP1AGER | |
| SCHEMBL6528502 | 0.80 | PPARA (0.37) | PPARAPPARDPPARGFBP1GPR119 | |
| SCHEMBL4681991 | 0.80 | PPARA (0.43) | PPARAPPARDPPARGAGERGPR119 | |
| SCHEMBL4679068 | 0.80 | PPARA (0.54) | PPARAPPARDPPARG | |
| SCHEMBL4682147 | 0.80 | PPARD (0.41) | PPARAPPARDPPARGFBP1 | |
| SCHEMBL14445913 | 0.77 | FBP1 (0.45) | PPARAPPARDPPARGFBP1 | |
| SCHEMBL4679129 | 0.76 | PPARD (0.42) | PPARAPPARDPPARGFBP1 | |
| SCHEMBL4677930 | 0.76 | PPARA (0.39) | PPARAPPARDPPARGFBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | claimed |
| EP-1513796-B1 | PHENYLOXYALKANOIC ACID DERIVATIVES AS HPPAR ACTIVATORS | SMITHKLINE BEECHAM CORP (US) | 2008-02-13 | — | — | EP | disclosed |
| US-7241793-B2 | Phenyloxyalkanonic acid derivatives as hPPAR activators | SMITHKLINE BEECHAM CORPORATION (US) | 2007-07-10 | — | — | US | disclosed |