SCHEMBL4682145

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4682138	0.89	ALDH1A1 (0.48)	ALDH1A1ALOX12MAPTLMNAMEN1
	SCHEMBL4680564	0.84	ALDH1A1 (0.53)	ALDH1A1ALOX12MAPTLMNAMEN1
	SCHEMBL4685945	0.83	NPSR1 (0.63)	ALDH1A1ALOX12MAPTLMNAMEN1
	SCHEMBL6672512	0.81	LMNA (0.53)	ALDH1A1ALOX12MAPTLMNAMEN1
	SCHEMBL4679775	0.81	LMNA (0.53)	ALDH1A1ALOX12MAPTLMNAMEN1
	SCHEMBL5212904	0.80	ALDH1A1 (0.56)	ALDH1A1ALOX12MAPTLMNAMEN1
	SCHEMBL4684022	0.79	KMT2A (0.63)	ALDH1A1ALOX12MAPTLMNAMEN1
	SCHEMBL4682172	0.78	MAPT (0.56)	ALDH1A1ALOX12MAPTLMNAMEN1
	SCHEMBL4683495	0.78	MAPT (0.51)	ALDH1A1ALOX12MAPTLMNAMEN1
	SCHEMBL4682188	0.78	ALDH1A1 (0.48)	ALDH1A1ALOX12MAPTLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.