Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PYGL | P06737 | 1/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 5/20 | 0.36 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.36 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SPTLC2 | O15270 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MTTP | P55157 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4682882 | 0.84 | PYGL (0.38) | SMN1; SMN2NPC1HPGDRAB9APYGL | |
| SCHEMBL4684494 | 0.81 | AVPR2 (0.38) | SMN1; SMN2NPC1HPGDRAB9APYGL | |
| SCHEMBL4682142 | 0.73 | AVPR2 (0.44) | PYGLAVPR2AVPR1AAVPR1BSPTLC2 | |
| SCHEMBL4682878 | 0.72 | AVPR2 (0.44) | SMN1; SMN2NPC1HPGDRAB9APYGL | |
| SCHEMBL4682873 | 0.72 | AVPR2 (0.45) | SMN1; SMN2NPC1HPGDRAB9APYGL | |
| SCHEMBL4684492 | 0.70 | AVPR2 (0.45) | SMN1; SMN2NPC1HPGDRAB9APYGL | |
| SCHEMBL4684483 | 0.70 | AVPR2 (0.46) | SMN1; SMN2NPC1HPGDRAB9APYGL | |
| SCHEMBL4687810 | 0.69 | AVPR2 (0.48) | SMN1; SMN2NPC1HPGDRAB9APYGL | |
| SCHEMBL7354620 | 0.67 | AVPR2 (0.53) | AVPR2AVPR1AAVPR1B | |
| SCHEMBL4684270 | 0.67 | AVPR2 (0.41) | SMN1; SMN2NPC1RAB9AAVPR2AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0620003-B1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMA CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |
| US-5622947-A | VASODILATORS, HYPOTENSIVE AGENTS, DIURETICS, PLATELET AGGLUTINATION INHIBITORS; ALSO USED TO PREVENT PREMATURE BIRTH, TREAT DYSMENORRHEA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |