Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PTGIR | P43119 | 7/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.40 |
| ▸ | CETP | P11597 | 3/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4738210 | 0.87 | RAB9A (0.40) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL2094984 | 0.85 | NPSR1 (0.48) | PTGIRPTGDRCETPPTGER4PTGER3 | |
| SCHEMBL2097683 | 0.85 | NPSR1 (0.48) | MTORMAOB | |
| SCHEMBL4678217 | 0.83 | ESR2 (0.49) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL2094545 | 0.81 | MEN1 (0.49) | MAOBPTGIR | |
| SCHEMBL14300675 | 0.80 | TACR1 (0.43) | PTGIRKCNN4 | |
| SCHEMBL4684462 | 0.80 | PTGIR (0.52) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL29116640 | 0.76 | TACR1 (0.51) | — | |
| SCHEMBL59388 | 0.75 | GRM4 (0.45) | PTGIRPTGDR | |
| SCHEMBL17504172 | 0.74 | MTOR (0.42) | MTORMAOBCETPOPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904446-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories Limited (IN) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007007282-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |