Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PTGIR | P43119 | 7/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4682247 | 0.87 | MTOR (0.48) | PTGIRPTGDRPTGER2PTGER4PTGER3 | |
| SCHEMBL4741127 | 0.84 | RAB9A (0.53) | RAB9AMEN1KMT2ANPSR1HTT | |
| SCHEMBL2094984 | 0.84 | NPSR1 (0.48) | RAB9AMEN1KMT2ANPSR1PTGIR | |
| SCHEMBL4678217 | 0.81 | ESR2 (0.49) | PTGIRPTGDRPTGER2PTGER4PTGER3 | |
| SCHEMBL4684462 | 0.78 | PTGIR (0.52) | PTGIRPTGDRPTGER2PTGER4PTGER3 | |
| SCHEMBL21173428 | 0.78 | KMT2A (0.37) | RAB9AMEN1KMT2ANPSR1HTT | |
| SCHEMBL7985347 | 0.74 | NPC1 (0.51) | RAB9AMEN1KMT2ANPSR1PTGIR | |
| SCHEMBL4681290 | 0.73 | RELA (0.45) | RAB9AMEN1KMT2APTGIRPTGDR | |
| SCHEMBL2094982 | 0.73 | PTGIR (0.47) | RAB9AMEN1KMT2ANPSR1PTGIR | |
| SCHEMBL2088335 | 0.72 | NPSR1 (0.50) | RAB9AMEN1KMT2ANPSR1PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904446-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | Ranbaxy Laboratories Limited (IN) | 2008-04-02 | — | — | EP | disclosed |
| WO-2007007282-A2 | AZABICYCLO DERIVATIVES AS MUSCARINIC RECEPTOR ANTAGONISTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-01-18 | — | — | WO | disclosed |