SCHEMBL468287

SCHEMBL468287

COc1ccc(C(=O)OOC(C)(C)C)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.65
ALDH1A1 P00352 2/20 0.65
TDP1 Q9NUW8 2/20 0.65
TSHR P16473 1/20 0.65
CA1 P00915 5/20 0.60
CA2 P00918 5/20 0.60
ELANE P08246 1/20 0.54
CES2 O00748 2/20 0.53
CES1 P23141 2/20 0.53
PARP1 P09874 1/20 0.50
PARP10 Q53GL7 1/20 0.50
PARP2 Q9UGN5 1/20 0.50
PARP4 Q9UKK3 1/20 0.50
MAPT P10636 2/20 0.49
KDM4E B2RXH2 1/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
MAPK1 P28482 2/20 0.47
LMNA P02545 2/20 0.47
ALOX15 P16050 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10977252 0.95 ALDH1A1 (0.59) HSD17B10ALDH1A1TDP1TSHRCA1
SCHEMBL2314112 0.89 CA1 (0.56) HSD17B10ALDH1A1TDP1TSHRCA1
SCHEMBL11126724 0.88 TSHR (0.80) HSD17B10ALDH1A1TDP1TSHRCA1
SCHEMBL296613 0.84 CA1 (0.75) CA1CA2CES2CES1PARP1
SCHEMBL476527 0.82 ALDH1A1 (0.71) HSD17B10ALDH1A1TDP1TSHRCA1
SCHEMBL2944672 0.82 NPC1 (0.51) HSD17B10ALDH1A1TDP1TSHRCA1
SCHEMBL30666384 0.81 ALDH1A1 (0.44) HSD17B10ALDH1A1TDP1TSHRCA1
SCHEMBL11064798 0.81 ELANE (0.67) HSD17B10ALDH1A1TDP1CA1CA2
SCHEMBL28647699 0.81 ALDH1A1 (0.75) HSD17B10ALDH1A1TDP1TSHRCA1
SCHEMBL8896071 0.81 ALDH1A1 (0.69) HSD17B10ALDH1A1TDP1TSHRCES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3253561-B1 PROCESS FOR PRODUCING MODIFIED OLEFIN POLYMER IN AN EXTRUDER BOREALIS AG (AT) 2019-05-08 EP claimed
US-10105908-B2 Process for producing modified olefin polymer in an extruder BOREALIS AG (AT) 2018-10-23 US claimed
US-20170361543-A1 Process for Producing Modified Olefin Polymer in an Extruder BOREALIS AG (AT) 2017-12-21 US claimed
WO-2016124617-A1 PROCESS FOR PRODUCING MODIFIED OLEFIN POLYMER IN AN EXTRUDER BOREALIS AG (AT) 2016-08-11 WO claimed
EP-4667512-A1 INCREASED AREA STRETCH RATIO FOR CAPACITOR FILMS MADE OF A BIAXIALLY ORIENTED POLYPROPYLENE FILM Borealis GmbH (AT) 2025-12-24 EP disclosed
EP-4086299-B1 THERMALLY TREATED BIAXIALLY ORIENTED POLYPROPYLENE FILM BOREALIS AG (AT) 2024-07-03 EP disclosed
EP-3898237-B1 BIAXIALLY ORIENTED POLYPROPYLENE FILM WITH IMPROVED SURFACE PROPERTIES BOREALIS AG (AT) 2024-04-17 EP disclosed
EP-3487927-B1 STIFF PROPYLENE COMPOSITION WITH GOOD DIMENSIONAL STABILITY AND EXCELLENT SURFACE APPEARANCE BOREALIS AG (AT) 2024-03-27 EP disclosed
EP-3532540-B1 HIGH FLOW HETEROPHASIC POLYPROPYLENE COPOLYMERS WITH IMPROVED MECHANICAL AND OPTICAL PROPERTIES BOREALIS AG (AT) 2024-03-13 EP disclosed
US-20230405969-A1 MULTILAYER SHEET COMPRISING A FOAMED LAYER SUITABLE FOR FOOD PACKAGING BOREALIS AG (AT) 2023-12-21 US disclosed
CN-117203269-A Biaxially oriented polypropylene film after heat treatment 博里利斯股份公司 2023-12-08 CN disclosed
US-20230227640-A1 POLYPROPYLENE COMPOSITION FOR HMS PP FOAM SHEET WITH BALANCED BENDING RESISTANCE BOREALIS AG (AT) 2023-07-20 US disclosed
EP-0915134-A2 Thermoplastic elastomer with high resistance, elasticity and good paintability and high impact resistant polymer blends prepared therefrom Borealis AG (AT) 1999-05-12 EP disclosed
EP-0884355-A1 Polyolefin foams with fine cells PCD Polymere AG (AT) 1998-12-16 EP disclosed
EP-0884335-A1 Segmented polyolefines PCD Polymere AG (AT) 1998-12-16 EP disclosed
EP-0821018-A2 Crosslinkable olefinic polymers and method for their preparation PCD-Polymere Gesellschaft m.b.H. (AT) 1998-01-28 EP disclosed
EP-0792894-A2 Continuous modification of polyolefins in solid phase PCD-Polymere Gesellschaft m.b.H. (AT) 1997-09-03 EP disclosed
EP-0787750-A2 Poly(alkylethylene) structural isomers PCD-Polymere Gesellschaft m.b.H. (AT) 1997-08-06 EP disclosed
US-4207288-A ANALYSIS OF PHOTOPOLYMERIZATION BY MEASUREMENT OF EXOTHERMIC REACTION ARMSTRONG CORK COMPANY (US) 1980-06-10 US disclosed
US-4171252-A Peroxy photoinitiator system for photopolymerizable compositions ARMSTRONG CORK COMPANY (US) 1979-10-16 US disclosed