SCHEMBL468288

SCHEMBL468288

CC(C)(C)COc1ccc(C(=O)OO)cc1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.49
PARP10 Q53GL7 3/20 0.44
RAB9A P51151 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.42
MAOB P27338 2/20 0.41
TDP1 Q9NUW8 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
GAA P10253 1/20 0.41
NPC1 O15118 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
NR4A2 P43354 2/20 0.40
RXRA P19793 2/20 0.40
RXRB P28702 2/20 0.40
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13366190 0.86 MAPT (0.68) MAPTRAB9AL3MBTL1TDP1SMN1; SMN2
SCHEMBL18997044 0.84 PARP10 (0.65) MAPTPARP10MAOBCA1CA2
SCHEMBL11505972 0.83 CA12 (0.56) MAPTRAB9AL3MBTL1TDP1SMN1; SMN2
SCHEMBL18026641 0.83 LMNA (0.51) MAPTPARP10MAOBSMN1; SMN2NR4A2
SCHEMBL2196744 0.81 NR4A2 (0.57) RAB9ASMN1; SMN2NPC1CA1CA2
SCHEMBL5789164 0.81 L3MBTL1 (0.63) MAPTRAB9AL3MBTL1MAOBSMN1; SMN2
SCHEMBL8726528 0.79 PARP10 (0.69) MAPTPARP10RAB9AMAOBGAA
SCHEMBL13141341 0.78 NQO1 (0.48) MAPTTDP1SMN1; SMN2
SCHEMBL14033180 0.77 PPARA (0.61) MAPTRAB9AL3MBTL1SMN1; SMN2GAA
SCHEMBL6538648 0.77 KMT2A (0.61) MAPTPARP10RAB9AL3MBTL1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 202 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3253561-B1 PROCESS FOR PRODUCING MODIFIED OLEFIN POLYMER IN AN EXTRUDER BOREALIS AG (AT) 2019-05-08 EP claimed
US-10105908-B2 Process for producing modified olefin polymer in an extruder BOREALIS AG (AT) 2018-10-23 US claimed
US-20170361543-A1 Process for Producing Modified Olefin Polymer in an Extruder BOREALIS AG (AT) 2017-12-21 US claimed
WO-2016124617-A1 PROCESS FOR PRODUCING MODIFIED OLEFIN POLYMER IN AN EXTRUDER BOREALIS AG (AT) 2016-08-11 WO claimed
EP-3487927-B1 STIFF PROPYLENE COMPOSITION WITH GOOD DIMENSIONAL STABILITY AND EXCELLENT SURFACE APPEARANCE BOREALIS AG (AT) 2024-03-27 EP disclosed
EP-3532540-B1 HIGH FLOW HETEROPHASIC POLYPROPYLENE COPOLYMERS WITH IMPROVED MECHANICAL AND OPTICAL PROPERTIES BOREALIS AG (AT) 2024-03-13 EP disclosed
US-20230405969-A1 MULTILAYER SHEET COMPRISING A FOAMED LAYER SUITABLE FOR FOOD PACKAGING BOREALIS AG (AT) 2023-12-21 US disclosed
US-20230227620-A1 HMS PP FOAM SHEET WITH GOOD COMPRESSIVE STRENGTH AND RECOVERABILITY BOREALIS AG (AT) 2023-07-20 US disclosed
US-20230227640-A1 POLYPROPYLENE COMPOSITION FOR HMS PP FOAM SHEET WITH BALANCED BENDING RESISTANCE BOREALIS AG (AT) 2023-07-20 US disclosed
EP-4172253-A1 POLYPROPYLENE COMPOSITION FOR HMS PP FOAM SHEET WITH BALANCED BENDING RESISTANCE Borealis AG (AT) 2023-05-03 EP disclosed
EP-4172254-A1 HMS PP FOAM SHEET WITH GOOD COMPRESSSIVE STRENGTH AND RECOVERABILITY Borealis AG (AT) 2023-05-03 EP disclosed
EP-3018156-B1 Branched polypropylene for foam applications BOREALIS AG (AT) 2023-03-22 EP disclosed
US-6225366-B1 USED IN PACKAGING SECTOR, MOTOR VEHICLE PARTS, SPORTS AND LEISURE EQUIPMENT, INDUSTRIAL APPLICATIONS, AS WELL AS APPLICATIONS IN THE BUILDING MATERIAL BOREALIS AG (AT) 2001-05-01 US disclosed
US-6218011-B1 Polyolefin fibers and polyolefin yarns and textile fabrics produced therefrom BOREALIS GMBH (AT) 2001-04-17 US disclosed
US-6204348-B1 REACTING A POLYPROPYLENE WITH ETHYLENICALLY UNSATURATED MONOMER BOREALIS GMBH (AT) 2001-03-20 US disclosed
US-6136926-A CURING WITH ETHYLENICALLY UNSATURATED ORGANOSILANE COMPOUND; HEATING BELOW SOFTENING POINT BOREALIS GMBH (AT) 2000-10-24 US disclosed
US-5962594-A Segmented polyolefins BOREALIS AG (AT) 1999-10-05 US disclosed
US-5929127-A Fine-celled polyolefin foam materials BOREALIS AG (AT) 1999-07-27 US disclosed
US-4207288-A ANALYSIS OF PHOTOPOLYMERIZATION BY MEASUREMENT OF EXOTHERMIC REACTION ARMSTRONG CORK COMPANY (US) 1980-06-10 US disclosed
US-4171252-A Peroxy photoinitiator system for photopolymerizable compositions ARMSTRONG CORK COMPANY (US) 1979-10-16 US disclosed