Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 7/20 | 0.51 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | PLD1 | Q13393 | 7/20 | 0.48 |
| ▸ | PLD2 | O14939 | 6/20 | 0.48 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3803735 | 0.90 | OPRM1 (0.49) | CHRM1PLD1PLD2CYP2D6OPRM1 | |
| SCHEMBL4682974 | 0.85 | CHRM1 (0.52) | CHRM1DRD2HTR1AADRA2AHTR2A | |
| SCHEMBL4682975 | 0.85 | CHRM1 (0.52) | CHRM1DRD2HTR1AADRA2AHTR2A | |
| SCHEMBL1840394 | 0.84 | OPRM1 (0.55) | CHRM1DRD2DRD3PLD1PLD2 | |
| SCHEMBL1833748 | 0.83 | OPRM1 (0.42) | CHRM1CYP2D6OPRM1CYP3A4OPRK1 | |
| SCHEMBL1839221 | 0.82 | OPRM1 (0.53) | DRD2HTR1AADRA2AHTR2ASLC6A4 | |
| SCHEMBL1835996 | 0.82 | OPRM1 (0.54) | CHRM1DRD2HTR1AADRA2AHTR2A | |
| SCHEMBL1833800 | 0.81 | BCHE (0.45) | CHRM1DRD2CYP2D6OPRM1OPRK1 | |
| SCHEMBL1833680 | 0.80 | OPRM1 (0.51) | CHRM1PLD1PLD2CYP2D6OPRM1 | |
| SCHEMBL4682970 | 0.78 | CHRM1 (0.52) | CHRM1DRD2HTR1AADRA2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1997805-A1 | Compounds with antiparasitic activity, applications thereof to the treatment of infectious diseases caused by apicomplexans | Commissariat à l'Energie Atomique (FR) | 2008-12-03 | — | — | EP | disclosed |