Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 12/20 | 0.54 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1839221 | 0.93 | OPRM1 (0.53) | OPRM1OPRK1OPRL1USP2CYP1A2 | |
| SCHEMBL1833680 | 0.93 | OPRM1 (0.51) | OPRM1CHRM1OPRK1OPRL1CYP2D6 | |
| SCHEMBL1836434 | 0.90 | OPRM1 (0.49) | OPRM1CHRM1OPRK1OPRL1PMP22 | |
| SCHEMBL1835708 | 0.89 | OPRM1 (0.57) | OPRM1CHRM1OPRK1OPRL1DRD2 | |
| SCHEMBL1839281 | 0.88 | CYP3A4 (0.49) | OPRM1OPRK1OPRL1PMP22CYP3A4 | |
| SCHEMBL1831375 | 0.88 | OPRM1 (0.52) | OPRM1OPRK1OPRL1PMP22KDM4E | |
| SCHEMBL1836588 | 0.88 | OPRM1 (0.51) | OPRM1CHRM1OPRK1OPRL1USP2 | |
| SCHEMBL3397204 | 0.88 | OPRM1 (0.47) | OPRM1CHRM1OPRK1OPRL1PMP22 | |
| SCHEMBL1832410 | 0.87 | HSD11B1 (0.45) | OPRM1CHRM1OPRK1OPRL1CYP2D6 | |
| SCHEMBL1836056 | 0.86 | OPRM1 (0.55) | OPRM1OPRK1OPRL1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2160098-B9 | USE OF COMPOUNDS HAVING A MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE INHIBITORY ACTIVITY AS HERBICIDE OR ALGAECIDE, HERBICIDE AND ALGAECIDE COMPOSITIONS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2011-05-18 | — | — | EP | claimed |
| EP-2160098-B1 | USE OF COMPOUNDS HAVING A MONOGALACTOSYLDIACYLGLYCEROL SYNTHASE INHIBITORY ACTIVITY AS HERBICIDE OR ALGAECIDE, HERBICIDE AND ALGAECIDE COMPOSITIONS | COMMISSARIAT ENERGIE ATOMIQUE (FR) | 2010-11-10 | — | — | EP | claimed |