Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 15/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 15/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 12/20 | 0.62 |
| ▸ | NOS2 | P35228 | 1/20 | 0.56 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4309799 | 0.87 | SLC6A2 (0.63) | SLC6A2SLC6A4SLC6A3NOS2CACNA1B | |
| SCHEMBL4305445 | 0.83 | SLC6A2 (0.60) | SLC6A2SLC6A4SLC6A3NOS2CACNA1B | |
| SCHEMBL4684474 | 0.80 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3NOS2CACNA1B | |
| SCHEMBL4242252 | 0.79 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3NOS2CCR5 | |
| SCHEMBL312704 | 0.78 | SLC6A4 (0.63) | SLC6A2SLC6A4SLC6A3NOS2 | |
| SCHEMBL312406 | 0.78 | SLC6A2 (0.65) | SLC6A2SLC6A4SLC6A3NOS2 | |
| SCHEMBL27815200 | 0.77 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3NOS2CACNA1B | |
| SCHEMBL4312492 | 0.77 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3NOS2CACNA1B | |
| SCHEMBL4306682 | 0.77 | NOS2 (0.62) | SLC6A2SLC6A4SLC6A3NOS2 | |
| SCHEMBL10108872 | 0.77 | SLC6A2 (0.61) | SLC6A2SLC6A4SLC6A3NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879887-A2 | NPY ANTAGONISTS, PREPARATION AND USE | Cerep (FR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006108965-A2 | NPY ANTAGONISTS, PREPARATION AND USE | CEREP (FR) | 2006-10-19 | — | — | WO | disclosed |