Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 9/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.46 |
| ▸ | AVPR1B | P47901 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7348955 | 0.94 | AVPR2 (0.55) | AVPR2MEN1KMT2AAVPR1AAVPR1B | |
| SCHEMBL7364823 | 0.89 | AVPR2 (0.48) | AVPR2TP53 | |
| SCHEMBL4687327 | 0.87 | AVPR2 (0.55) | AVPR2MEN1KMT2AAVPR1AAVPR1B | |
| SCHEMBL8632240 | 0.80 | AVPR2 (0.44) | AVPR2AVPR1AMAPTLMNA | |
| SCHEMBL8630825 | 0.80 | AVPR2 (0.40) | AVPR2MAPTUSP2ALDH1A1HSD17B10 | |
| SCHEMBL7354543 | 0.79 | AVPR2 (0.57) | AVPR2MEN1KMT2AAVPR1ATP53 | |
| SCHEMBL7352446 | 0.78 | AVPR2 (0.59) | AVPR2MEN1KMT2AAVPR1ATP53 | |
| Hydrochloric Acid SCHEMBL8628767 | 0.78 | AVPR2 (0.47) | AVPR2MEN1KMT2AAVPR1AMAPT | |
| SCHEMBL4687283 | 0.76 | AVPR2 (0.51) | AVPR2MEN1KMT2AAVPR1AAVPR1B | |
| Hydrochloric Acid SCHEMBL7338452 | 0.76 | AVPR2 (0.57) | AVPR2AVPR1AAVPR1BCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902717-A2 | Vasopressin antagonist and oxytocin antagonist | Otsuka Pharmaceutical Company, Limited (JP) | 2008-03-26 | — | — | EP | disclosed |
| EP-0620003-B1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMA CO LTD (JP) | 2008-01-16 | — | — | EP | disclosed |
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |
| US-5622947-A | VASODILATORS, HYPOTENSIVE AGENTS, DIURETICS, PLATELET AGGLUTINATION INHIBITORS; ALSO USED TO PREVENT PREMATURE BIRTH, TREAT DYSMENORRHEA | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-22 | — | — | US | disclosed |
| EP-0514667-B1 | Benzazepin derivatives as vasopressin antagonists | OTSUKA PHARMA CO LTD (JP) | 1995-08-09 | — | — | EP | disclosed |
| EP-0620003-A1 | VASOPRESSIN ANTAGONIST AND OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-19 | — | — | EP | disclosed |