Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 10/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 6/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8635109 | 0.90 | AVPR2 (0.44) | AVPR2AVPR1ACYP2C9HTR1A | |
| SCHEMBL8630825 | 0.85 | AVPR2 (0.40) | AVPR2HTR1ADRD2HTR2AABCB1 | |
| SCHEMBL8627388 | 0.83 | AVPR2 (0.45) | AVPR2AVPR1ACYP2C9ABCB1 | |
| SCHEMBL4687327 | 0.81 | AVPR2 (0.55) | AVPR2AVPR1AMAPTEPHX2 | |
| SCHEMBL4683205 | 0.80 | AVPR2 (0.52) | AVPR2AVPR1ALMNAMAPT | |
| SCHEMBL7348955 | 0.74 | AVPR2 (0.55) | AVPR2AVPR1ALMNAMAPT | |
| Hydrochloric Acid SCHEMBL7352307 | 0.71 | AVPR2 (0.61) | AVPR2AVPR1A | |
| SCHEMBL4687283 | 0.71 | AVPR2 (0.51) | AVPR2AVPR1AMAPT | |
| SCHEMBL7364823 | 0.70 | AVPR2 (0.48) | AVPR2 | |
| SCHEMBL4687300 | 0.69 | AVPR2 (0.43) | AVPR2AVPR1AHTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753644-A | Vasopressin antagonist and oxytocin antagonist | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-05-19 | — | — | US | disclosed |