Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 12/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4683205 | 0.89 | AVPR2 (0.52) | AVPR2TP53 | |
| SCHEMBL7348955 | 0.83 | AVPR2 (0.55) | AVPR2TP53 | |
| SCHEMBL4687327 | 0.79 | AVPR2 (0.55) | AVPR2TP53 | |
| SCHEMBL8632240 | 0.70 | AVPR2 (0.44) | AVPR2 | |
| SCHEMBL8630825 | 0.70 | AVPR2 (0.40) | AVPR2 | |
| Hydrochloric Acid SCHEMBL8628767 | 0.69 | AVPR2 (0.47) | AVPR2TP53TSHR | |
| SCHEMBL7017339 | 0.69 | AVPR2 (0.46) | AVPR2 | |
| SCHEMBL4685041 | 0.68 | CHRM5 (0.44) | AVPR2TP53 | |
| SCHEMBL4687283 | 0.68 | AVPR2 (0.51) | AVPR2 | |
| Hydrochloric Acid SCHEMBL7338452 | 0.68 | AVPR2 (0.57) | AVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0514667-A1 | Benzazepin derivatives as vasopressin antagonists | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-25 | — | — | EP | disclosed |